Centre for Regenerative Medicine & Stem Cell Research

2016

Mycobacterial contamination of bronchoscopes: Challenges and possible solutions in low resource settings

Saeed, D. K., Shakoor, S., Irfan, S. & Hasan, R., 1 Dec 2016, In: International Journal of Mycobacteriology. 5, 4, p. 408-411 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project

Zignol, M., Dean, A. S., Alikhanova, N., Andres, S., Cabibbe, A. M., Cirillo, D. M., Dadu, A., Dreyer, A., Driesen, M., Gilpin, C., Hasan, R., Hasan, Z., Hoffner, S., Husain, A., Hussain, A., Ismail, N., Kamal, M., Mansjö, M., Mvusi, L., Niemann, S., & 14 othersOmar, S. V., Qadeer, E., Rigouts, L., Ruesch-Gerdes, S., Schito, M., Seyfaddinova, M., Skrahina, A., Tahseen, S., Wells, W. A., Mukadi, Y. D., Kimerling, M., Floyd, K., Weyer, K. & Raviglione, M. C., 1 Oct 2016, In: The Lancet Infectious Diseases. 16, 10, p. 1185-1192 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

141 Citations (Scopus)

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

Phelan, J. E., Coll, F., Bergval, I., Anthony, R. M., Warren, R., Sampson, S. L., Gey van Pittius, N. C., Glynn, J. R., Crampin, A. C., Alves, A., Bessa, T. B., Campino, S., Dheda, K., Grandjean, L., Hasan, R., Hasan, Z., Miranda, A., Moore, D., Panaiotov, S., Perdigao, J., & 10 othersPortugal, I., Sheen, P., de Oliveira Sousa, E., Streicher, E. M., van Helden, P. D., Viveiros, M., Hibberd, M. L., Pain, A., McNerney, R. & Clark, T. G., 29 Feb 2016, In: BMC Genomics. 17, 1, 151.

Research output: Contribution to journal › Article › peer-review

Open Access

63 Citations (Scopus)

Sequelae of extrapulmonary tuberculosis after treatment: Addressing patient needs

Jamil, B., Shakoor, S. & Hasan, R., 1 Dec 2016, In: International Journal of Mycobacteriology. 5, p. S149

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

Tuberculosis in vulnerable populations in Eastern Mediterranean Region—Implications for control

Shakoor, S. & Hasan, R., 1 Dec 2016, In: International Journal of Mycobacteriology. 5, p. S15

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

2015

Characterization of genomic variations in SNPs of PE_PGRS genes reveals deletions and insertions in extensively drug resistant (XDR) M. tuberculosis strains from Pakistan

Kanji, A., Hasan, Z., Ali, A., McNerney, R., Mallard, K., Coll, F., Hill-Cawthorne, G., Nair, M., Clark, T. G., Zaver, A., Jafri, S. & Hasan, R., 1 Mar 2015, In: International Journal of Mycobacteriology. 4, 1, p. 73-79 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Etiology of bacteremia in young infants in six countries

Hamer, D. H., Darmstadt, G. L., Carlin, J. B., Zaidi, A. K. M., Yeboah-Antwi, K., Saha, S. K., Ray, P., Narang, A., Mazzi, E., Kumar, P., Kapil, A., Jeena, P. M., Deorari, A., Chowdury, A. K. A., Bartos, A., Bhutta, Z. A., Adu-Sarkodie, Y., Adhikari, M., Addo-Yobo, E., Weber, M. W., & 57 othersAzad Chowdhury, A. K., Nawshad Uddin Ahmed, A. S. M., Hossain, M. M., Nahar, N., Baidya, A., Parul, M., Islam, M., Nasreen, T., Rahaman, M. R., Villagomez, T., Mattos, P., Ludueña, M. P., Zumarán, R., Quispe, I., Tarqui, W., Checa, L., Canqui, C., Dueñas, E., Vargas, O., Yobo, E. A., Plange-Rhule, G., Akoto, O., Lartey, M., Akpene, H., Narang, R., Muley, P., Misra, S., Tapasaya, R. S., Gaur, T., Kanojia, V., Dogra, A., Chellani, H., Prasad, M. S., Satyavani, A., John, J. R., Negi, S., Singhal, N., Sunder, S., Sultana, S., Azeem, S., Lasi, R., Abbasi, F., Sultana, R., Jabbar, N. A., Hasan, R., Rizvi, A., Thaver, D., Mojaphelo, S., Sturm, W., Sikhakhane., P., Bahl, R., Mulholland, K., Paul, V., Simoes, E., Zupan, J., Greenwood, P. & Chionh, C., 2015, In: Pediatric Infectious Disease Journal. 34, 1, p. e1-e8

Research output: Contribution to journal › Article › peer-review

Open Access

84 Citations (Scopus)

Fluoroquinolone resistance in Mycobacterium tuberculosis isolates from Pakistan 2010-2014: Implications for disease control

Jabeen, K., Shakoor, S., Malik, F. & Hasan, R., 1 Mar 2015, In: International Journal of Mycobacteriology. 4, p. 47-48 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Citations (Scopus)

Fluoroquinolone-resistant tuberculosis: Implications in settings with weak healthcare systems

Jabeen, K., Shakoor, S. & Hasan, R., 2015, In: International Journal of Infectious Diseases. 32, p. 118-123 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Citations (Scopus)

Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Coll, F., McNerney, R., Preston, M. D., Guerra-Assunção, J. A., Warry, A., Hill-Cawthorne, G., Mallard, K., Nair, M., Miranda, A., Alves, A., Perdigão, J., Viveiros, M., Portugal, I., Hasan, Z., Hasan, R., Glynn, J. R., Martin, N., Pain, A. & Clark, T. G., 14 Dec 2015, In: Genome Medicine. 7, 1, 51.

Research output: Contribution to journal › Article › peer-review

Open Access

302 Citations (Scopus)

Whole genome sequencing based characterization of extensively drug-resistant mycobacterium tuberculosis isolates from pakistan

Ali, A., Hasan, Z., McNerney, R., Mallard, K., Hill-Cawthorne, G., Coll, F., Nair, M., Pain, A., Clark, T. G. & Hasan, R., 26 Feb 2015, In: PLoS ONE. 10, 2, e0117771.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Citations (Scopus)

2014

Expression of the Androgen Receptor, pAkt, and pPTEN in Breast Cancer and Their Potential in Prognostication

Sultana, A., Idress, R., Naqvi, Z. A., Azam, I., Khan, S., Siddiqui, A. A. & Lalani, E. N., Jun 2014, In: Translational Oncology. 7, 3, p. 355-362 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Citations (Scopus)

MP39-17 MECP2 Silencing in high grade bladder Cancer derived HTB-5 Cell line affects Cellular Proliferation and Migratory ability

Bilgrami, S., Naqvi, Z., Shaikh, K., Lalani, E-N. & Abbas, F., 1 Apr 2014, In: Department of Pathology and Laboratory Medicine.

Research output: Contribution to journal › Article

Mycobacterium tuberculosis Central Asian Strain (CAS) lineage strains in Pakistan reveal lower diversity of MIRU loci than other strains

Ali, A., Hasan, Z., Jafri, S., Inayat, R. & Hasan, R., Jun 2014, In: International Journal of Mycobacteriology. 3, 2, p. 108-116 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Citations (Scopus)

2013

Identification of non-tuberculous mycobacteria isolated from clinical specimens at a tertiary care hospital: A cross-sectional study

Ahmed, I., Jabeen, K. & Hasan, R., 22 Oct 2013, In: BMC Infectious Diseases. 13, 1, 493.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

Susceptibility testing of extensively drug-resistant and pre-xtensively drug-resistant mycobacterium tuberculosis against levofloxacin, linezolid, and amoxicillin-clavulanate

Ahmed, I., Jabeen, K., Inayat, R. & Hasan, R., Jun 2013, In: Antimicrobial Agents and Chemotherapy. 57, 6, p. 2522-2525 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Citations (Scopus)

Unusual sex differences in tuberculosis notifications across Pakistan and the role of environmental factors

Khan, M. S., Khan, M. S., Hasan, R. & Godfrey-Faussett, P., Sept 2013, In: Eastern Mediterranean Health Journal. 19, 9, p. 821-825 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

2012

Characterizing Mycobacterium tuberculosis isolates from Karachi, Pakistan: Drug resistance and genotypes

Ayaz, A., Hasan, Z., Jafri, S., Inayat, R., Mangi, R., Channa, A. A., Malik, F. R., Ali, A., Rafiq, Y. & Hasan, R., Apr 2012, In: International Journal of Infectious Diseases. 16, 4, p. e303-e309

Research output: Contribution to journal › Article › peer-review

Open Access

41 Citations (Scopus)

Line probe assay for detection of rifampicin and isoniazid resistant tuberculosis in Pakistan.

Farooqi, J. Q., Khan, E., Alam, S. M. Z., Ali, A., Hasan, Z. & Hasan, R., Aug 2012, In: Unknown Journal. 62, 8, p. 767-772 6 p.

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Macrolide and fluoroquinolone resistance in Helicobacter pylori isolates: An experience at a tertiary care centre in Pakistan

Rajper, S., Khan, E., Ahmad, Z., Alam, S. M. Z., Akbar, A. & Hasan, R., Nov 2012, In: Journal of the Pakistan Medical Association. 62, 11, p. 1140-1144 5 p.

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Multidrug resistant Mycobacterium tuberculosis amongst Category I & II failures and Category II relapse patients from Pakistan

Ghafoor, A., Mehraj, J., Afridi, N. D., Rafiq, Y., Wendl-Richter, H. U. & Hasan, R., Sept 2012, In: International Journal of Mycobacteriology. 1, 3, p. 118-123 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

Overcoming drug-resistant tuberculosis

Hasan, R., Hasan, Z. & Tahseen, S., 2012, In: European Infectious Disease. 6, 2, p. 87-93 7 p.

Research output: Contribution to journal › Article › peer-review

Risk factors for multidrug-resistant tuberculosis in urban Pakistan: A multicenter case-control study

Ahmad, A. M., Akhtar, S., Hasan, R., Khan, J. A., Hussain, S. F. & Rizvi, N., Sept 2012, In: International Journal of Mycobacteriology. 1, 3, p. 137-142 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Citations (Scopus)

Species identification of invasive yeasts including Candida in Pakistan: Limitations of phenotypic methods

Farooqi, J., Jabeen, K., Saeed, N., Zafar, A., Brandt, M. E. & Hasan, R., Oct 2012, In: Journal of the Pakistan Medical Association. 62, 10, p. 995-998 4 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

2011

Characterization of mutations conferring extensive drug resistance to Mycobacterium tuberculosis isolates in Pakistan

Ali, A., Hasan, R., Jabeen, K., Jabeen, N., Qadeer, E. & Hasan, Z., Dec 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5654-5659 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Citations (Scopus)

Cohort analysis of directly observed treatment outcomes for tuberculosis patients in urban Pakistan

Akhtar, S., Rozi, S., White, F. & Hasan, R., Jan 2011, In: International Journal of Tuberculosis and Lung Disease. 15, 1, p. 90-96 7 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Fluoroquinolone resistance among Mycobacterium tuberculosis strains from Karachi, Pakistan: Data from community-based field clinics

Rafiq, Y., Jabeen, K., Hasan, R., Jafri, S., Laiq, R., Malik, F., Mangi, R., Channa, A. & Hasan, Z., Feb 2011, In: Antimicrobial Agents and Chemotherapy. 55, 2, p. 929-930 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Genetic regulation of the ramA locus and its expression in clinical isolates of Klebsiella pneumoniae

Rosenblum, R., Khan, E., Gonzalez, G., Hasan, R. & Schneiders, T., Jul 2011, In: International Journal of Antimicrobial Agents. 38, 1, p. 39-45 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Citations (Scopus)

Molecular and epidemiological characterisation of clinical isolates of carbapenem-resistant Acinetobacter baumannii from public and private sector intensive care units in Karachi, Pakistan

Irfan, S., Turton, J. F., Mehraj, J., Siddiqui, S. Z., Haider, S., Zafar, A., Memon, B., Afzal, O. & Hasan, R., Jun 2011, In: Journal of Hospital Infection. 78, 2, p. 143-148 6 p.

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Mycobacterium tuberculosis genotypes in patients developing pulmonary tuberculosis related acute respiratory distress syndrome

Salahuddin, N., Tanveer, M. T., Rao, N. A., Akram, S., Hasan, Z. & Hasan, R., 1 Nov 2011, In: Department of Pathology and Laboratory Medicine.

Research output: Contribution to journal › Article

Occurrence of RD149 and RD152 deletions in Mycobacterium tuberculosis strains from Pakistan

Kanji, A., Hasan, Z., Tanveer, M., Laiq, R. & Hasan, R., Feb 2011, In: Journal of Infection in Developing Countries. 5, 2, p. 106-113 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

Presence of RD149 deletions in m. tuberculosis central Asian strain 1 isolates affect growth and TNFalpha induction in THP-1 monocytes.

Kanji, A., Hasan, Z., Tanveer, M., Mahboob, R., Jafri, S. & Hasan, R., 31 Aug 2011, In: Department of Pathology and Laboratory Medicine.

Research output: Contribution to journal › Article

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8 Downloads (Pure)

Presence of RD149 deletions in M. tuberculosis Central Asian Strain1 isolates affect growth and TNFα induction in THP-1 monocytes

Kanji, A., Hasan, Z., Tanveer, M., Mahboob, R., Jafri, S. & Hasan, R., 2011, In: PLoS ONE. 6, 8, e24178.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

2010

Clonal dissemination of vanA positive Enterococcus species in tertiary care hospitals in Karachi, Pakistan

Fasih, N., Zafar, A., Khan, E., Jabeen, K. & Hasan, R., Oct 2010, In: Journal of the Pakistan Medical Association. 60, 10, p. 805-809 5 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Demographic and clinical features of dengue fever in Pakistan from 2003-2007: A retrospective cross- sectional study

Khan, E., Kisat, M., Khan, N., Nasir, A., Ayub, S. & Hasan, R., 2010, In: PLoS ONE. 5, 9, p. 1-7 7 p., e12505.

Research output: Contribution to journal › Article › peer-review

Open Access

98 Citations (Scopus)

Doxazosin induces apoptosis in PTEN-positive androgen-independent PC cells via inhibition of Akt activation

Romanska, H., Salagierski, M., Bruton, R., Abel, P., Sosnowski, M. & Lalani, E. N., 2010, In: Central European Journal of Urology. 63, 2, p. 91-97 7 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Emergence of CTX-M Group 1-ESBL producing Klebsiella pneumonia from a tertiary care centre in Karachi, Pakistan

Khan, E., Schneiders, T., Zafar, A., Aziz, E., Parekh, A. & Hasan, R., Aug 2010, In: Journal of Infection in Developing Countries. 4, 8, p. 472-476 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Citations (Scopus)

Extensively drug-resistant tuberculosis, Pakistan

Hasan, R., Jabeen, K., Ali, A., Rafiq, Y., Laiq, R., Malik, B., Tanveer, M., Groenheit, R., Ghebremichael, S., Hoffner, S. & Hasan, Z., 2010, In: Emerging Infectious Diseases. 16, 9, p. 1473-1475 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Citations (Scopus)

Increased isolation of ESBL producing Klebsiella pneumoniae with emergence of carbapenem resistant isolates in Pakistan: Report from a tertiary care hospital

Khan, E., Ejaz, M., Zafar, A., Jabeen, K., Shakoor, S., Inayat, R. & Hasan, R., Mar 2010, In: Journal of the Pakistan Medical Association. 60, 3, p. 186-190 5 p.

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Increase in isolation of extended spectrum beta lactamase producing multidrug resistant non typhoidal Salmonellae in Pakistan

Jabeen, K., Zafar, A., Irfan, S., Khan, E., Mehraj, V. & Hasan, R., 22 Apr 2010, In: BMC Infectious Diseases. 10, 101.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Citations (Scopus)

Inducible clindamycin resistance due to expression of erm genes in Staphylococcus aureus: Report from a tertiary care hospital Karachi, Pakistan

Fasih, N., Irfan, S., Zafar, A., Khan, E. & Hasan, R., 2010, In: Journal of the Pakistan Medical Association. 60, 9, p. 750-753 4 p.

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

In vitro activity of tigecycline and other tetracyclines against carbapenem-resistant acinetobacter species: Report from a tertiary care centre in Karachi, Pakistan

Shakoor, S., Khan, E., Zafar, A. & Hasan, R., Jun 2010, In: Chemotherapy. 56, 3, p. 184-189 6 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Prevalence of multi-drug resistant tuberculosis in Karachi, Pakistan: identification of at risk groups

Ejaz, M., Siddiqui, A. R., Rafiq, Y., Malik, F., Channa, A., Mangi, R., Habib, F. & Hasan, R., Aug 2010, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 104, 8, p. 511-517 7 p.

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Use of p-nitrobenzoic acid in 7H10 agar for identification of Mycobacterium tuberculosis complex: A field study

Shakoor, S., Ahsan, T., Jabeen, K., Raza, M. & Hasan, R., Dec 2010, In: International Journal of Tuberculosis and Lung Disease. 14, 12, p. 1644-1646 3 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2009

CD151 regulates tumorigenesis by modulating the communication between tumor cells and endothelium

Sadej, R., Romanska, H., Baldwin, G., Gkirtzimanaki, K., Novitskaya, V., Filer, A. D., Krcova, Z., Kusinska, R., Ehrmann, J., Buckley, C. D., Kordek, R., Potemski, P., Eliopoulos, A. G., Lalani, E. N. & Berditchevski, F., Jun 2009, In: Molecular Cancer Research. 7, 6, p. 787-798 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Citations (Scopus)

Controlled evaluation of bactec Peds Plus/F and bactec lytic/10 anaerobic/F media for isolation of salmonella enterica serovars typhi and paratyphi a from blood

Reller, M. E., Zaidi, A. K. M., Sultana, S., Azeem, S., Hanif, B., Qureshi, S., Hasan, R., Bhutta, Z., Akhter, R. & Goldmann, D. A., Jan 2009, In: Journal of Clinical Microbiology. 47, 1, p. 245-246 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

Evaluation of two ELISA Assay Kits against RT-PCR for diagnosis of Dengue Virus Infection in a Hospital Setting in Karachi, Pakistan

Khan, E., Mehraj, V., Nasir, A., Khan, N. A., Billoo, B., Moatter, T. & Hasan, R., Jun 2009, In: Journal of the Pakistan Medical Association. 59, 6, p. 390-394 5 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Frequency of isolation of various subtypes and antimicrobial resistance of Shigella from urban slums of Karachi, Pakistan

Zafar, A., Hasan, R., Nizami, S. Q., von Seidlein, L., Soofi, S., Ahsan, T., Chandio, S., Habib, A., Bhutto, N., Siddiqui, F. J., Rizvi, A., Clemens, J. D. & Bhutta, Z. A., Nov 2009, In: International Journal of Infectious Diseases. 13, 6, p. 668-672 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Citations (Scopus)

Infection control education: Impact on ventilator-associated pneumonia rates in a public sector intensive care unit in Pakistan

Khan, M. S., Siddiqui, S. Z., Haider, S., Zafar, A., Zafar, F., Khan, R. N., Afshan, K., Jabeen, A., Khan, M. S. & Hasan, R., Aug 2009, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 103, 8, p. 807-811 5 p.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

M. tuberculosis Central Assian Strain 1 MDR isolates have more mutations in rpoB and katG genes compared with other genotypes

Ali, A., Hasan, Z., Moatter, T., Tanveer, M. & Hasan, R., 2009, In: Scandinavian Journal of Infectious Diseases. 41, 1, p. 37-44 8 p.

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Centre for Regenerative Medicine & Stem Cell Research

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