A biochemical test based on pyrazinamidase activity for rapid differentiation of corynebacteria

G. Revathi; V. Talwar

doi:10.1007/BF02873667

A biochemical test based on pyrazinamidase activity for rapid differentiation of corynebacteria

Research output: Contribution to journal › Article › peer-review

Abstract

A simple, rapid and inexpensive test is described based on the activity of the enzyme pyrazinamidase, which hydrolyses pyrazinamide to pyrazinoic acid. This test differentiates most of the corynebacteria possessing this enzyme from the exotoxin producing human pathogenic members of this group, i.e., C. diphtheriae, C. ulcerans and C. pseudotuberculosis, which do not produce this enzyme. In our laboratory, 16 isolates of C. diphtheriae and 75 isolates of non-diphtheric corynebacteria were rapidly identified, over the past three years.

Original language	English
Pages (from-to)	39-41
Number of pages	3
Journal	Indian Journal of Clinical Biochemistry
Volume	10
Issue number	1
DOIs	https://doi.org/10.1007/BF02873667
Publication status	Published - Jan 1995
Externally published	Yes

Keywords

Corynebacteria
Diphtheria
Pyrazinamidase test

Access to Document

10.1007/BF02873667

Cite this

@article{742c683d34e94eaaa196113125f6012d,

title = "A biochemical test based on pyrazinamidase activity for rapid differentiation of corynebacteria",

abstract = "A simple, rapid and inexpensive test is described based on the activity of the enzyme pyrazinamidase, which hydrolyses pyrazinamide to pyrazinoic acid. This test differentiates most of the corynebacteria possessing this enzyme from the exotoxin producing human pathogenic members of this group, i.e., C. diphtheriae, C. ulcerans and C. pseudotuberculosis, which do not produce this enzyme. In our laboratory, 16 isolates of C. diphtheriae and 75 isolates of non-diphtheric corynebacteria were rapidly identified, over the past three years.",

keywords = "Corynebacteria, Diphtheria, Pyrazinamidase test",

author = "G. Revathi and V. Talwar",

year = "1995",

month = jan,

doi = "10.1007/BF02873667",

language = "English",

volume = "10",

pages = "39--41",

journal = "Indian Journal of Clinical Biochemistry",

issn = "0970-1915",

publisher = "Springer India",

number = "1",

}

TY - JOUR

T1 - A biochemical test based on pyrazinamidase activity for rapid differentiation of corynebacteria

AU - Revathi, G.

AU - Talwar, V.

PY - 1995/1

Y1 - 1995/1

N2 - A simple, rapid and inexpensive test is described based on the activity of the enzyme pyrazinamidase, which hydrolyses pyrazinamide to pyrazinoic acid. This test differentiates most of the corynebacteria possessing this enzyme from the exotoxin producing human pathogenic members of this group, i.e., C. diphtheriae, C. ulcerans and C. pseudotuberculosis, which do not produce this enzyme. In our laboratory, 16 isolates of C. diphtheriae and 75 isolates of non-diphtheric corynebacteria were rapidly identified, over the past three years.

AB - A simple, rapid and inexpensive test is described based on the activity of the enzyme pyrazinamidase, which hydrolyses pyrazinamide to pyrazinoic acid. This test differentiates most of the corynebacteria possessing this enzyme from the exotoxin producing human pathogenic members of this group, i.e., C. diphtheriae, C. ulcerans and C. pseudotuberculosis, which do not produce this enzyme. In our laboratory, 16 isolates of C. diphtheriae and 75 isolates of non-diphtheric corynebacteria were rapidly identified, over the past three years.

KW - Corynebacteria

KW - Diphtheria

KW - Pyrazinamidase test

UR - http://www.scopus.com/inward/record.url?scp=0029123677&partnerID=8YFLogxK

U2 - 10.1007/BF02873667

DO - 10.1007/BF02873667

M3 - Article

AN - SCOPUS:0029123677

SN - 0970-1915

VL - 10

SP - 39

EP - 41

JO - Indian Journal of Clinical Biochemistry

JF - Indian Journal of Clinical Biochemistry

IS - 1

ER -

A biochemical test based on pyrazinamidase activity for rapid differentiation of corynebacteria

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this