A brief review of skull base chordomas

Syeda Kubra Kishwar Jafri, Ahsan Ali Khan, Duarte Nuno Crispim Cândido, Muhammad Shahzad Shamim

Research output: Contribution to journalArticlepeer-review


Skull base chrodomas are slow growing neoplasms usually located along the midline. They display a locally invasive nature with possibilities of extracranial metastasis. Presentation is usually late and depends upon the location and extent of the tumour. Management aims at gross total resection via open microsurgical or endoscopic approach followed by adjuvant radiotherapy. Prognosis may be good for the classical and chondroid subtypes but remains poor for de-differentiated type.

Original languageEnglish
Pages (from-to)2495-2498
Number of pages4
JournalJournal of the Pakistan Medical Association
Issue number12
Publication statusPublished - Dec 2023


  • Chordoma
  • radiotherapy
  • skull base
  • surgical management


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