A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection

Abdul Ahad Sohail; Bushra Ayub; Syed Akbar Abbas; Shafqat Ali Sheikh; Talha Ahmed Qureshi; Muhammad Usman; Asad Diwan

doi:10.1016/j.amsu.2020.07.023

A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection

Abdul Ahad Sohail, Bushra Ayub, Syed Akbar Abbas, Shafqat Ali Sheikh, Talha Ahmed Qureshi, Muhammad Usman, Asad Diwan

Section of Otolaryngology, Head & Neck Surgery, Department of Surgery, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

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Abstract

Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease free survival period without adjuvant chemotherapy or radiotherapy.

Original language	English (UK)
Pages (from-to)	62-65
Number of pages	4
Journal	Annals of Medicine and Surgery
Volume	57
DOIs	https://doi.org/10.1016/j.amsu.2020.07.023
Publication status	Published - Sept 2020

Keywords

Complete surgical resection
Parathyroid carcinomas
Primary hyperparathyroidism
Thyroid lobectomy

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.amsu.2020.07.023

Cite this

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title = "A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection",

abstract = "Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005\% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60\% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease free survival period without adjuvant chemotherapy or radiotherapy.",

keywords = "Complete surgical resection, Parathyroid carcinomas, Primary hyperparathyroidism, Thyroid lobectomy",

author = "Sohail, \{Abdul Ahad\} and Bushra Ayub and Abbas, \{Syed Akbar\} and Sheikh, \{Shafqat Ali\} and Qureshi, \{Talha Ahmed\} and Muhammad Usman and Asad Diwan",

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month = sep,

doi = "10.1016/j.amsu.2020.07.023",

language = "English (UK)",

volume = "57",

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journal = "Annals of Medicine and Surgery",

issn = "2049-0801",

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T1 - A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection

AU - Sohail, Abdul Ahad

AU - Ayub, Bushra

AU - Abbas, Syed Akbar

AU - Sheikh, Shafqat Ali

AU - Qureshi, Talha Ahmed

AU - Usman, Muhammad

AU - Diwan, Asad

PY - 2020/9

Y1 - 2020/9

N2 - Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease free survival period without adjuvant chemotherapy or radiotherapy.

AB - Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease free survival period without adjuvant chemotherapy or radiotherapy.

KW - Complete surgical resection

KW - Parathyroid carcinomas

KW - Primary hyperparathyroidism

KW - Thyroid lobectomy

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DO - 10.1016/j.amsu.2020.07.023

M3 - Article

AN - SCOPUS:85088133679

SN - 2049-0801

VL - 57

SP - 62

EP - 65

JO - Annals of Medicine and Surgery

JF - Annals of Medicine and Surgery

ER -

A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection

Abstract

Keywords

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