TY - JOUR
T1 - A survey of Asian Eye Institutions on perioperative antibiotic prophylaxis in cataract surgery
AU - For the APAX consortium
AU - Garg, Prashant
AU - Khor, Wei Boon
AU - Roy, Aravind
AU - Tan, Donald Tiang Hwee
AU - Ke, Yao
AU - Zhu, Xiangjia
AU - Young, Alvin L.
AU - Aravind, Haripriya
AU - Sharma, Namrata
AU - Heryati, Susi
AU - Hutauruk, Johan A.
AU - Sitompul, Ratna
AU - Nishida, Kohji
AU - Oie, Yoshinori
AU - Yamaguchi, Takefumi
AU - Kamal, Khairidzan Mohd
AU - Jeeva, Irfan
AU - Abaño, Jessica Marie R.
AU - Siong, Ruben Lim Bon
AU - Hyon, Joon Young
AU - Seo, Kyoung Yul
AU - Chang, Shu Wen
AU - Hu, Fung Rong
AU - Liu, Catherine Jui Ling
AU - Sun, Chi Chin
AU - Kasetsuwan, Ngamjit
AU - Prabhasawat, Pinnita
AU - Cung, Le Xuan
AU - Nguyen, Quoc Dat
N1 - Publisher Copyright:
© 2023, The Author(s).
PY - 2023
Y1 - 2023
N2 - Purpose: To determine current institutional practice patterns for the use of perioperative antibiotics and other measures to prevent infection after cataract surgery in Asia. Methods: An online survey-based study of leading eye institutions in China, Hong Kong, India, Indonesia, Japan, Malaysia, Pakistan, Philippines, Singapore, South Korea, Taiwan, Thailand and Vietnam was conducted. The survey was administered to 26 representative key opinion leaders from prominent tertiary eye institutions that are also national academic teaching institutions in Asia. Survey responses were collated and anonymized during analysis. Results: All surveyed institutions used povidone iodine for the preoperative antiseptic preparation of the eye, with notable variations in the concentration of povidone iodine used for conjunctival sac instillation. Preoperative topical antibiotics were prescribed by 61.5% and 69.2% of institutions in low-risk and high-risk cases, respectively. Regarding the use of intra-operative antibiotics, 60.0% and 66.7% of institutions administered intracameral antibiotics in low-risk and high-risk patients, respectively. Postoperative topical antibiotics use patterns were generally very similar in low-risk and high-risk patients. Over half of the institutions (52.2% and 68.0% in low-risk and high-risk patients, respectively) also indicated prolonged postoperative use of topical antibiotics (> 2 weeks). Not all surveyed institutions had established policies/protocols for perioperative antibiotic use in cataract surgery, endophthalmitis surveillance, and/or a monitoring program for emerging antimicrobial resistance. Conclusion: There are variations in antimicrobial prophylaxis approaches to preoperative, intra-operative and postoperative regimens in cataract surgery in Asia. More evidence-based research is needed to support the development of detailed guidelines for perioperative antibiotic prophylaxis to reduce postoperative infections.
AB - Purpose: To determine current institutional practice patterns for the use of perioperative antibiotics and other measures to prevent infection after cataract surgery in Asia. Methods: An online survey-based study of leading eye institutions in China, Hong Kong, India, Indonesia, Japan, Malaysia, Pakistan, Philippines, Singapore, South Korea, Taiwan, Thailand and Vietnam was conducted. The survey was administered to 26 representative key opinion leaders from prominent tertiary eye institutions that are also national academic teaching institutions in Asia. Survey responses were collated and anonymized during analysis. Results: All surveyed institutions used povidone iodine for the preoperative antiseptic preparation of the eye, with notable variations in the concentration of povidone iodine used for conjunctival sac instillation. Preoperative topical antibiotics were prescribed by 61.5% and 69.2% of institutions in low-risk and high-risk cases, respectively. Regarding the use of intra-operative antibiotics, 60.0% and 66.7% of institutions administered intracameral antibiotics in low-risk and high-risk patients, respectively. Postoperative topical antibiotics use patterns were generally very similar in low-risk and high-risk patients. Over half of the institutions (52.2% and 68.0% in low-risk and high-risk patients, respectively) also indicated prolonged postoperative use of topical antibiotics (> 2 weeks). Not all surveyed institutions had established policies/protocols for perioperative antibiotic use in cataract surgery, endophthalmitis surveillance, and/or a monitoring program for emerging antimicrobial resistance. Conclusion: There are variations in antimicrobial prophylaxis approaches to preoperative, intra-operative and postoperative regimens in cataract surgery in Asia. More evidence-based research is needed to support the development of detailed guidelines for perioperative antibiotic prophylaxis to reduce postoperative infections.
KW - Asia
KW - Cataract
KW - Infection
KW - Perioperative
KW - Prophylaxis
UR - http://www.scopus.com/inward/record.url?scp=85166757814&partnerID=8YFLogxK
U2 - 10.1007/s10792-023-02816-w
DO - 10.1007/s10792-023-02816-w
M3 - Article
C2 - 37526782
AN - SCOPUS:85166757814
SN - 0165-5701
JO - International Ophthalmology
JF - International Ophthalmology
ER -