A unique MRI presentation of fungal infection in the brain

Muhammad Bilal Salman Khan, Saad Shafqat, Syed Ather Enam

Research output: Contribution to journalArticlepeer-review


Fungal infections of CNS are common in certain geographic locations. MRI with or without contrast is a useful prediagnostic tool. However, the findings may sometimes be misleading. In this case report, the authors present unusual imaging findings in the MRI of fungal infection in an immunocompetent host, whereby hyper-intense signals were seen on T2-weighted images and patchy post-contrast enhancement was observed with surrounding edema. These findings were suggestive of a neoplastic lesion but it was identified as aspergillosis on subsequent histopathology. This unusual MRI finding of CNS highlights the need to consider fungal infection as a differential diagnosis of all mass lesions on MRI, irrespective of their signal characteristics.

Original languageEnglish
Pages (from-to)S211-S213
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Publication statusPublished - 2014


  • Aspergillosis
  • Brain
  • Fungal infection
  • T2-weighted hyperintense signal


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