Abscopal Effect: An Old Concept with a New Horizon

Ahmed Nadeem Abbasi, Agha Muhammad Hammad Khan, Muhammad Atif Mansha, Fatima Shaukat, Rabia Tahseen

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Abscopal effect is defined as a phenomenon where radiation delivery at one site induces shrinkage of disease at a distant site, outside the radiation field. Although it is an old concept but with recent advancements in the fields of diagnostic and therapeutic oncology, this effect has gained popularity and nowadays has become an area of interest for the researchers.With the current success of immunotherapy, there is robust and interesting data looming to evaluate potential synergistic effect of radiation coupled with immunotherapy to attain abscopal effect. Our article highlights background, mechanism and a brief literature review for abscopal response in conjunction with immunotherapy. Keywords: Abscopal Effect, Radiation, Immunotherapy, Personalized Medicine.

Original languageEnglish
Pages (from-to)60-66
Number of pages7
JournalThe gulf journal of oncology
Volume1
Issue number36
Publication statusPublished - 1 May 2021
Externally publishedYes

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