Absence of the Y chromosome in patients with chronic granulocytic leukaemia

J. A. Whittaker, P. Davies, M. Khurshid

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

The Y chromosome was missing from the cells of aspirated bone marrow in 2 patients with chronic granulocytic leukaemia (CGL). In both cases, blast cell transformation occurred within 17 months of presentation. Their short course is in contrast to the hypothesis that absence of the Y chromosome in CGL is compatible with long survival.

Original languageEnglish
Pages (from-to)350-357
Number of pages8
JournalActa Haematologica
Volume54
Issue number6
DOIs
Publication statusPublished - 1975
Externally publishedYes

Keywords

  • Chronic granulocytic leukaemia
  • Karyotype
  • Y chromosome

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