Acute necrotizing encephalopathy of childhood: A fatal complication of swine flu

Muhammad Rehan Khan, Prem Kumar Maheshwari, Syed Asad Ali, Anwarul Haque

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Acute necrotizing encephalopathy of childhood (ANEC) is a rare condition characterized by the presence of multifocal symmetrical brain lesions involving mainly thalami, brainstem, cerebellum and white matter. ANEC is a serious and life threatening complication of simple viral infections. We present a case of a young child who developed this condition with classical clinical and radiological findings consistent with ANEC, secondary to swine flu (H1N1). He needed ventilatory support and had profound motor and intellectual deficit on discharge. We report this case with aim of raising awareness about this fatal complication of swine flu which has become a global health care issue these days.

Original languageEnglish
Pages (from-to)119-120
Number of pages2
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number2
Publication statusPublished - Feb 2011


  • Acute necrotizing encephalopathy
  • Brainstem
  • Cerebellum
  • Children
  • Swine flu
  • Symmetrical brain lesions
  • Thalami
  • White matter


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