Amiodarone therapy: Don't forget thyroid

Maseeh-uz-Zaman, Nosheen Fatima, Zafar Sajjad

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


Amiodarone is an effective anti-arrhythmic agent for control of various life threatening ventricular tachyarrhythmias but may give various side effects. Clinically relevant thyroid dysfunction is not uncommon during amiodarone therapy and is caused by iodide excess and inhibition of deiodinase activity. Amiodarone induced thyroid dysfunction varies from asymptomatic variation in thyroid function to clinically overt hypothyroidism and thyrotoxicosis. Prolonged elimination and half life and associated complications warrant for rational prescribing andlong term follow up.

Original languageEnglish
Pages (from-to)268-272
Number of pages5
JournalJournal of the Pakistan Medical Association
Issue number3
Publication statusPublished - Mar 2012


  • Amiodarone
  • Hypothyroidism
  • Thyroid disorder
  • Thyrotoxicosis
  • Wolff-chaikoff effect


Dive into the research topics of 'Amiodarone therapy: Don't forget thyroid'. Together they form a unique fingerprint.

Cite this