Abstract
This study describes the antisecretory and analgesic activities of the crude extract of Terminalia bellerica (Tb.Cr). T. bellerica extract inhibited the castor oil-induced intestinal fluid secretion in mice at the dose range of 300 - 1000 mg/kg. The extract also dose-dependently (50 - 100 mg/kg) reduced the numbers of acetic acid-mediated writhes in mice. These results indicate that T. bellerica exhibit antisecretory and anti-nociceptive effects, hence justifying its medicinal use in diarrhea and pain.
| Original language | English (UK) |
|---|---|
| Pages (from-to) | 2717-2719 |
| Number of pages | 3 |
| Journal | African Journal of Biotechnology |
| Volume | 9 |
| Issue number | 18 |
| Publication status | Published - 3 May 2010 |
| Externally published | Yes |
Keywords
- Analgesia
- Intestinal secretion
- Terminalia bellerica
