Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Saad B. Omer; Robert Bednarczyk; Momin Kazi; L. Beryl Guterman; Fatima Aziz; Kristen E. Allen; Inci Yildirim; S. Asad Ali

doi:10.1097/INF.0000000000002159

Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Saad B. Omer, Robert Bednarczyk, Momin Kazi, L. Beryl Guterman, Fatima Aziz, Kristen E. Allen, Inci Yildirim, S. Asad Ali

Department of Paediatrics and Child Health, Division of Woman and Child Health, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.

Original language	English
Pages (from-to)	E57-E59
Journal	Pediatric Infectious Disease Journal
Volume	38
Issue number	3
DOIs	https://doi.org/10.1097/INF.0000000000002159
Publication status	Published - 1 Mar 2019

Keywords

RSV
surveillance
syndromic case definition

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/INF.0000000000002159

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title = "Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population",

abstract = "Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of {"}wheeze or apnea or cyanosis{"} could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.",

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AU - Bednarczyk, Robert

AU - Kazi, Momin

AU - Beryl Guterman, L.

AU - Aziz, Fatima

AU - Allen, Kristen E.

AU - Yildirim, Inci

AU - Asad Ali, S.

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AB - Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.

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Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Abstract

Keywords

UN SDGs

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