Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Saad B. Omer, Robert Bednarczyk, Momin Kazi, L. Beryl Guterman, Fatima Aziz, Kristen E. Allen, Inci Yildirim, S. Asad Ali

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.

Original languageEnglish
Pages (from-to)E57-E59
JournalPediatric Infectious Disease Journal
Volume38
Issue number3
DOIs
Publication statusPublished - 1 Mar 2019

Keywords

  • RSV
  • surveillance
  • syndromic case definition

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