Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Saad B. Omer; Robert Bednarczyk; Momin Kazi; L. Beryl Guterman; Fatima Aziz; Kristen E. Allen; Inci Yildirim; S. Asad Ali

doi:10.1097/INF.0000000000002159

Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Saad B. Omer
, Robert Bednarczyk
, Momin Kazi
, L. Beryl Guterman
, Fatima Aziz
, Kristen E. Allen
, Inci Yildirim
, S. Asad Ali

Department of Paediatrics and Child Health, Division of Woman and Child Health, Medical College, Pakistan
Department of Community Health Sciences, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.

Original language	English (US)
Pages (from-to)	E57-E59
Journal	Pediatric Infectious Disease Journal
Volume	38
Issue number	3
DOIs	https://doi.org/10.1097/INF.0000000000002159
Publication status	Published - 1 Mar 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

RSV
surveillance
syndromic case definition

Access to Document

10.1097/INF.0000000000002159

Cite this

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title = "Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population",

abstract = "Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of {"}wheeze or apnea or cyanosis{"} could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2\%-49.6\%), indicating that community-based surveillance may need augmentation with other data.",

keywords = "RSV, surveillance, syndromic case definition",

author = "Omer, \{Saad B.\} and Robert Bednarczyk and Momin Kazi and \{Beryl Guterman\}, L. and Fatima Aziz and Allen, \{Kristen E.\} and Inci Yildirim and \{Asad Ali\}, S.",

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AU - Omer, Saad B.

AU - Bednarczyk, Robert

AU - Kazi, Momin

AU - Beryl Guterman, L.

AU - Aziz, Fatima

AU - Allen, Kristen E.

AU - Yildirim, Inci

AU - Asad Ali, S.

PY - 2019/3/1

Y1 - 2019/3/1

N2 - Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.

AB - Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.

KW - RSV

KW - surveillance

KW - syndromic case definition

UR - https://www.scopus.com/pages/publications/85061509380

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M3 - Article

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AN - SCOPUS:85061509380

SN - 0891-3668

VL - 38

SP - E57-E59

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 3

ER -

Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Abstract

UN SDGs

Keywords

Access to Document

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