Abstract
Objective: To determine the association of Macrolide, use and hearing loss in young adults. Study design: Quasi-experimental study. Place and Duration of Study: ENT Head and Neck Surgery Department Combined Military Hospital, Rawalpindi, Pakistan from May 2023 to Oct 2023. Methodology: A total of 54 patients fulfilling the selection criteria were enrolled after taking written informed consent and were divided into two Groups of 27 patients each. Group I consisted of patients with history of Macrolide use, Group II with history of Penicillin use. Sensorineural Hearing Loss (SNHL) was assessed in both Groups and findings were statistically analyzed. Results: The mean age of the patients was 25.27±3.08 years, the mean duration of symptom was 7.33±2.71 days. There were 30(55.6%) males and 24(44.4%) females in the study. SNHL was reported in 6(11.1%) patients. In Group I, 4(14.8%) patients developed SNHL compared to 2(7.4%) patients in Group II. SNHL rate was higher in Macrolide Group. Conclusion: The frequency of developing SNHL was found twice in patients who received Macrolide compared to Penicillin Group.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1240-1244 |
| Number of pages | 5 |
| Journal | Pakistan Armed Forces Medical Journal |
| Volume | 75 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2025 |
| Externally published | Yes |
Keywords
- Hearing loss
- Macrolide
- Penicillin
- Sensorineural Hearing Loss
