Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh

Ahmed Abbaskhan, Muhammed Iqbal Choudhary, Mohammed Nabeel Ghayur, Zeba Parween, Farzana Shaheen, Anwar Ul Hassan Gilani, Takuro Maruyama, Kiran Iqbal, Yoshisuke Tsuda

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh; Umbelliferae), the fractionation of the 80% MeOH-H2O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant.

Original languageEnglish
Pages (from-to)783-786
Number of pages4
JournalPhytotherapy Research
Issue number5
Publication statusPublished - May 2012
Externally publishedYes


  • Indian celery
  • Seseli diffusum
  • antioxidant activity
  • cytotoxicity
  • spasmogenic activity
  • spasmolytic activity


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