Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh

Ahmed Abbaskhan; Muhammed Iqbal Choudhary; Mohammed Nabeel Ghayur; Zeba Parween; Farzana Shaheen; Anwar Ul Hassan Gilani; Takuro Maruyama; Kiran Iqbal; Yoshisuke Tsuda

doi:10.1002/ptr.3600

Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh

Ahmed Abbaskhan, Muhammed Iqbal Choudhary, Mohammed Nabeel Ghayur, Zeba Parween, Farzana Shaheen, Anwar Ul Hassan Gilani, Takuro Maruyama, Kiran Iqbal, Yoshisuke Tsuda

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh; Umbelliferae), the fractionation of the 80% MeOH-H₂O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant.

Original language	English (UK)
Pages (from-to)	783-786
Number of pages	4
Journal	Phytotherapy Research
Volume	26
Issue number	5
DOIs	https://doi.org/10.1002/ptr.3600
Publication status	Published - May 2012
Externally published	Yes

Keywords

Indian celery
Seseli diffusum
antioxidant activity
cytotoxicity
spasmogenic activity
spasmolytic activity

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10.1002/ptr.3600

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@article{285e0bf4579348508f678a0531c86e56,

title = "Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. \& Wagh",

abstract = "In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau \& Wagh; Umbelliferae), the fractionation of the 80\% MeOH-H2O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant.",

keywords = "Indian celery, Seseli diffusum, antioxidant activity, cytotoxicity, spasmogenic activity, spasmolytic activity",

author = "Ahmed Abbaskhan and Choudhary, \{Muhammed Iqbal\} and Ghayur, \{Mohammed Nabeel\} and Zeba Parween and Farzana Shaheen and Gilani, \{Anwar Ul Hassan\} and Takuro Maruyama and Kiran Iqbal and Yoshisuke Tsuda",

year = "2012",

month = may,

doi = "10.1002/ptr.3600",

language = "English (UK)",

volume = "26",

pages = "783--786",

journal = "Phytotherapy Research",

issn = "0951-418X",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh

AU - Abbaskhan, Ahmed

AU - Choudhary, Muhammed Iqbal

AU - Ghayur, Mohammed Nabeel

AU - Parween, Zeba

AU - Shaheen, Farzana

AU - Gilani, Anwar Ul Hassan

AU - Maruyama, Takuro

AU - Iqbal, Kiran

AU - Tsuda, Yoshisuke

PY - 2012/5

Y1 - 2012/5

N2 - In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh; Umbelliferae), the fractionation of the 80% MeOH-H2O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant.

AB - In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh; Umbelliferae), the fractionation of the 80% MeOH-H2O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant.

KW - Indian celery

KW - Seseli diffusum

KW - antioxidant activity

KW - cytotoxicity

KW - spasmogenic activity

KW - spasmolytic activity

UR - https://www.scopus.com/pages/publications/84859911278

U2 - 10.1002/ptr.3600

DO - 10.1002/ptr.3600

M3 - Article

C2 - 22095902

AN - SCOPUS:84859911278

SN - 0951-418X

VL - 26

SP - 783

EP - 786

JO - Phytotherapy Research

JF - Phytotherapy Research

IS - 5

ER -

Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh

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Keywords

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