Breast development and disorders in children and adolescents

Fatima Mubarak, Ayesha Malick, Abida K. Sattar

Research output: Contribution to journalArticlepeer-review


Breast masses are infrequently encountered in pediatric and adolescent populations. Most breast masses in children are benign entities arising from embryological defects which can be managed once breast development is complete. Diagnostic and management dilemmas arise when fibroepithelial lesions of the breast are seen in clinical practice. Differentiation between a fibroadenoma and a phyllodes tumor is important to guide management. Breast cancer in children under 18 years of age is extremely rare and invasive diagnostic testing and aggressive management is only recommended when clinical suspicion of malignancy is very high. Patient and caregiver counseling plays an important role in the management of these diseases. While adult-onset breast diseases have been studied very closely, there is a dearth of literature on pediatric breast anomalies. This review aims to provide a scoping overview of the available literature on benign, fibroepithelial, and malignant lesions of the breast in pediatric and adolescent populations to help guide physicians and surgeons with decision-making regarding the diagnosis and management of pediatric breast diseases.

Original languageEnglish
Article number101441
JournalCurrent Problems in Pediatric and Adolescent Health Care
Issue number7
Publication statusPublished - Jul 2023


  • Fibroadenoma
  • Fibroepithelial breast lesions
  • Pediatric breast cancer
  • Pediatric breast masses
  • Phyllodes tumor


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