Calcifying fibrous pseudotumour of maxilla: A rare entity mimicking malignancy: A case report

Talha Ahmed Qureshi, Shabbir Akhtar, Mariam Abid

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Occurrence of inflammatory pseudotumour in head and neck region or nose and paranasal sinuses is rare. However, when they do occur, they could be quite aggressive. Etiologically, they are believed to be reactive than neoplastic, and calcification may suggest end-stage. Their clinical presentation and radiologic features may resemble a malignancy. Grossly, they are not encapsulated, but multilobulated and can be circumscribed or infiltrative. Histologically, they constitute of bland spindle cells with scant cytoplasm and occasional mitotic figures. Scattered lymphocytic and plasma cell infiltrates with abundant dense hyalinized collagenous stroma and focal small calcifications are seen. Presence of atypia, DNA aneuploidy, and abnormal p53 expression may suggest malignant potential. Though not known to metastasize, they can lead to local complications, causing destruction of bone and surrounding tissues. Management is mainly by surgical excision though adjunct corticosteroids have been advocated. We report such a rare case of calcifying fibrous pseudotumour of maxilla.

Original languageEnglish
Pages (from-to)1521-1524
Number of pages4
JournalJournal of the Pakistan Medical Association
Issue number10
Publication statusPublished - Oct 2018


  • Case reports
  • Case study
  • Inflammatory pseudotumor
  • Maxilla
  • Plasma cell granuloma


Dive into the research topics of 'Calcifying fibrous pseudotumour of maxilla: A rare entity mimicking malignancy: A case report'. Together they form a unique fingerprint.

Cite this