CARRS Surveillance study: Design and methods to assess burdens from multiple perspectives

  • Manisha Nair
  • , Mohammed K. Ali
  • , Vamadevan S. Ajay
  • , Roopa Shivashankar
  • , Viswanathan Mohan
  • , Rajendra Pradeepa
  • , Mohan Deepa
  • , Hassan M. Khan
  • , Muhammad M. Kadir
  • , Zafar A. Fatmi
  • , K. Srinath Reddy
  • , Nikhil Tandon
  • , K. M.Venkat Narayan
  • , Dorairaj Prabhakaran

Research output: Contribution to journalReview articlepeer-review

118 Citations (Scopus)

Abstract

Background: Cardio-metabolic diseases (CMDs) are a growing public health problem, but data on incidence, trends, and costs in developing countries is scarce. Comprehensive and standardised surveillance for non-communicable diseases was recommended at the United Nations High-level meeting in 2011. Aims: To develop a model surveillance system for CMDs and risk factors that could be adopted for continued assessment of burdens from multiple perspectives in South-Asian countries. Methods. Design: Hybrid model with two cross-sectional serial surveys three years apart to monitor trend, with a three-year prospective follow-up of the first cohort. Sites: Three urban settings (Chennai and New Delhi in India; Karachi in Pakistan), 4000 participants in each site stratified by gender and age. Sampling methodology: Multi-stage cluster random sampling; followed by within-household participant selection through a combination of Health Information National Trends Study (HINTS) and Kish methods. Culturally-appropriate and methodologically-relevant data collection instruments were developed to gather information on CMDs and their risk factors; quality of life, health-care utilisation and costs, along with objective measures of anthropometric, clinical and biochemical parameters. The cohort follow-up is designed as a pilot study to understand the feasibility of estimating incidence of risk factors, disease events, morbidity, and mortality. Results: The overall participant response rate in the first cross-sectional survey was 94.1% (Chennai 92.4%, n=4943; Delhi 95.7%, n=4425; Karachi 94.3%, n=4016). 51.8% of the participants were females, 61.6%<45years, 27.5% 45-60years and 10.9% >60years. Discussion. This surveillance model will generate data on prevalence and trends; help study the complex life-course patterns of CMDs, and provide a platform for developing and testing interventions and tools for prevention and control of CMDs in South-Asia. It will also help understanding the challenges and opportunities in establishing a surveillance system across countries.

Original languageEnglish (US)
Article number701
JournalBMC Public Health
Volume12
Issue number1
DOIs
Publication statusPublished - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cardio-metabolic diseases
  • Risk-factors
  • South-Asia
  • Surveillance

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