Celiac crisis in refractory celiac disease type I with neurological manifestations: A diagnostic dilemma

Ayesha Aslam Rai, Muhammad Osama Butt, Syed Mudassir Laeeq, Zaigham Abbas, Nasir Hasasan Luck, Syed Mujahid Hassan, Abbas Ali Tasneem, Muhammad Mubarak

Research output: Contribution to journalArticlepeer-review

Abstract

Celiac crisis is a life-threatening condition in which patients have profuse diarrhea and severe metabolic disturbances. Refractory Celiac Disease (RCD) is a rare condition defined as persistence of symptoms despite being on Gluten Free Diet (GFD) for 6 months. Neurological involvement in Celiac Disease (CD) is seen in around 8 - 10% of adult patients; however, it is rare in children. Herein we present a case of an adolescent presenting with neurological symptoms and celiac crisis and diagnosed as RCD, type 1. He was treated with high dose steroids. This case underscores the need to consider RCD in patients presenting in celiac crisis and showing no improvement on GFD.

Original languageEnglish
Pages (from-to)S134-S136
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Volume25
Publication statusPublished - 1 Oct 2015
Externally publishedYes

Keywords

  • Adolescent
  • Celiac crisis
  • Celiac disease
  • Gluten-free diet
  • Neurological complications

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