Central mucoepidermoid carcinoma, A case report with molecular analysis of the TORC1/MAML2 gene fusion

Haseeb Ahmed Khan; Asif Loya; Rafay Azhar; Nasir Ud Din; Diana Bell

doi:10.1007/s12105-010-0191-5

Central mucoepidermoid carcinoma, A case report with molecular analysis of the TORC1/MAML2 gene fusion

Haseeb Ahmed Khan, Asif Loya, Rafay Azhar, Nasir Ud Din, Diana Bell

Department of Pathology and Laboratory Medicine, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Mucoepidermoid carcinoma is the most common salivary gland malignancy. The majorities of these tumors arise in the parotid and minor salivary glands, but may rarely develop intraosseously. The latter is not uncommonly associated with diagnostic and management difficulties. We report an example of intraosseous mucoepidermoid carcinoma with positive TORC1/MAML2 gene fusion transcript and discuss the clinical implications.

Original language	English (US)
Pages (from-to)	261-264
Number of pages	4
Journal	Head and Neck Pathology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1007/s12105-010-0191-5
Publication status	Published - 2010

Keywords

Central mucoepidermoid carcinoma
Fusion genes
Intraosseous
Mandible
Molecular analysis
Odontogenic cyst
Salivary gland tumors
TORC1/MAML2

Access to Document

10.1007/s12105-010-0191-5

Cite this

@article{062bd6ac312a44b3ae58ab09b8f504d5,

title = "Central mucoepidermoid carcinoma, A case report with molecular analysis of the TORC1/MAML2 gene fusion",

abstract = "Mucoepidermoid carcinoma is the most common salivary gland malignancy. The majorities of these tumors arise in the parotid and minor salivary glands, but may rarely develop intraosseously. The latter is not uncommonly associated with diagnostic and management difficulties. We report an example of intraosseous mucoepidermoid carcinoma with positive TORC1/MAML2 gene fusion transcript and discuss the clinical implications.",

keywords = "Central mucoepidermoid carcinoma, Fusion genes, Intraosseous, Mandible, Molecular analysis, Odontogenic cyst, Salivary gland tumors, TORC1/MAML2",

author = "Khan, \{Haseeb Ahmed\} and Asif Loya and Rafay Azhar and Din, \{Nasir Ud\} and Diana Bell",

year = "2010",

doi = "10.1007/s12105-010-0191-5",

language = "English (US)",

volume = "4",

pages = "261--264",

journal = "Head and Neck Pathology",

issn = "1936-055X",

publisher = "Humana Press",

number = "3",

}

TY - JOUR

T1 - Central mucoepidermoid carcinoma, A case report with molecular analysis of the TORC1/MAML2 gene fusion

AU - Khan, Haseeb Ahmed

AU - Loya, Asif

AU - Azhar, Rafay

AU - Din, Nasir Ud

AU - Bell, Diana

PY - 2010

Y1 - 2010

N2 - Mucoepidermoid carcinoma is the most common salivary gland malignancy. The majorities of these tumors arise in the parotid and minor salivary glands, but may rarely develop intraosseously. The latter is not uncommonly associated with diagnostic and management difficulties. We report an example of intraosseous mucoepidermoid carcinoma with positive TORC1/MAML2 gene fusion transcript and discuss the clinical implications.

AB - Mucoepidermoid carcinoma is the most common salivary gland malignancy. The majorities of these tumors arise in the parotid and minor salivary glands, but may rarely develop intraosseously. The latter is not uncommonly associated with diagnostic and management difficulties. We report an example of intraosseous mucoepidermoid carcinoma with positive TORC1/MAML2 gene fusion transcript and discuss the clinical implications.

KW - Central mucoepidermoid carcinoma

KW - Fusion genes

KW - Intraosseous

KW - Mandible

KW - Molecular analysis

KW - Odontogenic cyst

KW - Salivary gland tumors

KW - TORC1/MAML2

UR - https://www.scopus.com/pages/publications/77955849501

U2 - 10.1007/s12105-010-0191-5

DO - 10.1007/s12105-010-0191-5

M3 - Article

C2 - 20625861

AN - SCOPUS:77955849501

SN - 1936-055X

VL - 4

SP - 261

EP - 264

JO - Head and Neck Pathology

JF - Head and Neck Pathology

IS - 3

ER -

Central mucoepidermoid carcinoma, A case report with molecular analysis of the TORC1/MAML2 gene fusion

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this