TY - JOUR
T1 - Cerebellar Mutism Syndrome after surgical resection of posterior fossa neoplastic lesions
AU - Bakhshi, Saqib Kamran
AU - Mitha, Rida
AU - Mushtaq, Naureen
AU - Shamim, Muhammad Shahzad
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Cerebellar Mutism Syndrome (CMS) is a well-described clinical entity that complicates surgeries for posterior fossa tumours; more so in children than adults. This review focuses on the current understanding of CMS, its incidence and risk factors. Incidence showed a variable range in retrospective studies due to variety of definitions. Risk factors can be classified as either modifiable including surgical technique, or non-modifiable which include tumour related factors. A positive correlation has been associated between tumour pathology, brain stem invasion and size of tumour at time of presentation with development of CMS.
AB - Cerebellar Mutism Syndrome (CMS) is a well-described clinical entity that complicates surgeries for posterior fossa tumours; more so in children than adults. This review focuses on the current understanding of CMS, its incidence and risk factors. Incidence showed a variable range in retrospective studies due to variety of definitions. Risk factors can be classified as either modifiable including surgical technique, or non-modifiable which include tumour related factors. A positive correlation has been associated between tumour pathology, brain stem invasion and size of tumour at time of presentation with development of CMS.
KW - Pediatric brain tumors, cerebellar mutism syndrome, posterior fossa syndrome
UR - http://www.scopus.com/inward/record.url?scp=85092752425&partnerID=8YFLogxK
M3 - Review article
C2 - 33040137
AN - SCOPUS:85092752425
SN - 0030-9982
VL - 70
SP - 1667
EP - 1668
JO - JPMA. The Journal of the Pakistan Medical Association
JF - JPMA. The Journal of the Pakistan Medical Association
IS - 9
ER -