TY - JOUR
T1 - Cerebral venous sinus thrombosis
AU - Yadollahikhales, Golnaz
AU - Borhani-Haghighi, Afshin
AU - Safari, Anahid
AU - Wasay, Mohammad
AU - Edgell, Randall
N1 - Publisher Copyright:
© 2013, Galen Medical Journal.
PY - 2016
Y1 - 2016
N2 - Cerebral venous thrombosis (CVT) is occlusion of dural sinuses and/or cortical veins due to clot formation. It is a potentially life-threatening condition that requires rapid diagnosis and urgent treatment. Cerebral venous thrombosis is more common in females and young people. Pregnancy, postpartum state, contraceptive pills, infection, malignancy, hyper-coagulable state, rheumatological disorders, trauma are among the major etiologies of cerebral venous thrombosis. Headache, focal neurologic deficits and seizure were the most common clinical presentations. Different techniques of unenhanced and contrast enhanced brain computerized tomography (CT scan) and, magnetic resonance imaging (MRI) are the most helpful ancillary investigations for diagnosis of Cerebral venous thrombosis. Specific treatment of the underlying cause of cerebral venous thrombosis should be considered as the mainstay of the treatment. Anticoagulation with heparin or low molecular weight heparinoids is the most accepted treatment. In acute phase, medical or surgical management to decrease intracranial pressure (ICP) is also recommended. If the patient's clinical condition aggravates despite adequate anticoagulation, thrombolysis or mechanical thrombectomy can be an additive option.
AB - Cerebral venous thrombosis (CVT) is occlusion of dural sinuses and/or cortical veins due to clot formation. It is a potentially life-threatening condition that requires rapid diagnosis and urgent treatment. Cerebral venous thrombosis is more common in females and young people. Pregnancy, postpartum state, contraceptive pills, infection, malignancy, hyper-coagulable state, rheumatological disorders, trauma are among the major etiologies of cerebral venous thrombosis. Headache, focal neurologic deficits and seizure were the most common clinical presentations. Different techniques of unenhanced and contrast enhanced brain computerized tomography (CT scan) and, magnetic resonance imaging (MRI) are the most helpful ancillary investigations for diagnosis of Cerebral venous thrombosis. Specific treatment of the underlying cause of cerebral venous thrombosis should be considered as the mainstay of the treatment. Anticoagulation with heparin or low molecular weight heparinoids is the most accepted treatment. In acute phase, medical or surgical management to decrease intracranial pressure (ICP) is also recommended. If the patient's clinical condition aggravates despite adequate anticoagulation, thrombolysis or mechanical thrombectomy can be an additive option.
KW - Cerebral venous thrombosis
KW - Hypercoagulable disorders
KW - Stroke
KW - Virchow's triad
UR - http://www.scopus.com/inward/record.url?scp=85052973839&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85052973839
SN - 2322-2379
VL - 5
SP - 48
EP - 61
JO - Galen Medical Journal
JF - Galen Medical Journal
IS - Specialissue
ER -