Cerebral venous sinus thrombosis in a patient with undiagnosed Factor VII deficiency

Hira Qadir, Anila Rashid, Salman Naseem Adil

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1 Citation (Scopus)

Abstract

Factor VII (FVII) deficiency is one of the rare inherited bleeding disorders. Thrombosis has been occasionally described in inherited FVII deficiency. Here, we report a young female with undiagnosed FVII deficiency who presented with cerebral venous sinus thrombosis (CVST). Oral contraceptive pill was found to be prothrombotic risk factor. The CVST occurred in spite of the congenital FVII deficiency indicating that no definitive antithrombotic protection is assured by this defect. Low molecular weight heparin and anti-Xa assay were found to be safe choice of anticoagulation and monitoring, respectively, in this patient.

Original languageEnglish
Pages (from-to)S86-S88
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Volume27
Publication statusPublished - 1 Sept 2017

Keywords

  • Cerebral venous sinus
  • Factor VII
  • Thrombosis

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