Abstract
Factor VII (FVII) deficiency is one of the rare inherited bleeding disorders. Thrombosis has been occasionally described in inherited FVII deficiency. Here, we report a young female with undiagnosed FVII deficiency who presented with cerebral venous sinus thrombosis (CVST). Oral contraceptive pill was found to be prothrombotic risk factor. The CVST occurred in spite of the congenital FVII deficiency indicating that no definitive antithrombotic protection is assured by this defect. Low molecular weight heparin and anti-Xa assay were found to be safe choice of anticoagulation and monitoring, respectively, in this patient.
| Original language | English (UK) |
|---|---|
| Pages (from-to) | S86-S88 |
| Journal | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP |
| Volume | 27 |
| Publication status | Published - 1 Sept 2017 |
Keywords
- Cerebral venous sinus
- Factor VII
- Thrombosis