TY - JOUR
T1 - Challenges and Special Aspects of Pulmonary Hypertension in Middle- to Low-Income Regions
T2 - JACC State-of-the-Art Review
AU - the European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, CSC, PASCAR, PCS, and PCSI
AU - Hasan, Babar
AU - Hansmann, Georg
AU - Budts, Werner
AU - Heath, Alexandra
AU - Hoodbhoy, Zahra
AU - Jing, Zhi Cheng
AU - Koestenberger, Martin
AU - Meinel, Katharina
AU - Mocumbi, Ana Olga
AU - Radchenko, Ganna D.
AU - Sallmon, Hannes
AU - Sliwa, Karen
AU - Kumar, R. Krishna
N1 - Publisher Copyright:
© 2020 The Authors
PY - 2020/5/19
Y1 - 2020/5/19
N2 - Challenges and special aspects related to the management and prognosis of pulmonary hypertension (PH) in middle- to low-income regions (MLIRs) range from late presentation to comorbidities, lack of resources and expertise, cost, and rare options of lung transplantation. Expert consensus recommendations addressing the specific challenges for prevention and therapy of PH in MLIRs with limited resources have been lacking. To date, 6 MLIR-PH registries containing mostly adult patients with PH exist. Importantly, the global prevalence of PH is much higher in MLIRs compared with high-income regions: group 2 PH (left heart disease), pulmonary arterial hypertension associated with unrepaired congenital heart disease, human immunodeficiency virus, or schistosomiasis are highly prevalent. This consensus statement provides selective, tailored modifications to the current PH guidelines to address the specific challenges faced in MLIRs, resulting in the first pragmatic and cost-effective consensus recommendations for PH care providers, patients, and their families.
AB - Challenges and special aspects related to the management and prognosis of pulmonary hypertension (PH) in middle- to low-income regions (MLIRs) range from late presentation to comorbidities, lack of resources and expertise, cost, and rare options of lung transplantation. Expert consensus recommendations addressing the specific challenges for prevention and therapy of PH in MLIRs with limited resources have been lacking. To date, 6 MLIR-PH registries containing mostly adult patients with PH exist. Importantly, the global prevalence of PH is much higher in MLIRs compared with high-income regions: group 2 PH (left heart disease), pulmonary arterial hypertension associated with unrepaired congenital heart disease, human immunodeficiency virus, or schistosomiasis are highly prevalent. This consensus statement provides selective, tailored modifications to the current PH guidelines to address the specific challenges faced in MLIRs, resulting in the first pragmatic and cost-effective consensus recommendations for PH care providers, patients, and their families.
KW - consensus statement
KW - middle- and low-income countries
KW - pulmonary hypertension
UR - http://www.scopus.com/inward/record.url?scp=85084786934&partnerID=8YFLogxK
U2 - 10.1016/j.jacc.2020.03.047
DO - 10.1016/j.jacc.2020.03.047
M3 - Review article
C2 - 32408981
AN - SCOPUS:85084786934
SN - 0735-1097
VL - 75
SP - 2463
EP - 2477
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 19
ER -