Coexistence of celiac and Crohn's disease in a patient presenting with chronic diarrhea

Ghulamullah Lail, Abbas Ali Tasneem, Muhammed Osama Butt, Nasir Hassan Luck, Syed Mudassir Laeq, Zaigham Abbas, Muhammed Mubarak

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Celiac disease (CD) is one of the most common causes of malabsorption. It is an immune-mediated disease manifested by diarrhea, steatorrhea, flatulence, and weight loss, caused by ingestion of gluten containing diets. The disease has typical small intestinal biopsy features of villous atrophy, crypt hyperplasia, and intense inflammation of the mucosal layer. The disease is rarely associated with Crohn's disease (CRD). Studies on the impact of CD on the natural history of inflammatory bowel disease (IBD) have shown that the natural course of CRD is not influenced by coexistent CD. We report a case of 54-year female who presented with diarrhea and weight loss. On initial evaluation, CD was diagnosed, and responded to gluten-free diet (GFD). Later on, she developed joint pains and her diarrhea recurred. Further evaluation revealed coexistence of CRD. The treatment of CRD was also initiated and this led to marked improvement in the symptoms of the patient.

Original languageEnglish
Pages (from-to)536-538
Number of pages3
JournalJournal of the College of Physicians and Surgeons--Pakistan : JCPSP
Issue number6
Publication statusPublished - 2016
Externally publishedYes


  • Celiac disease
  • Chronic diarrhea
  • Crohn's disease
  • Gluten-free diet


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