Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries

Pakistan Brain Tumour Consortium

Research output: Contribution to journalArticlepeer-review

Abstract

The posterior fossa is a limited compartment therefore lesions compressing its structures can result in devastating outcomes. It can cause significant neurological deficit due to mass effect on critical structures and hydrocephalus. Due to the nature of the infratentorial region, urgent surgical intervention is often the first-line option. Surgical neuro-oncologists guide patients and caregivers through the course of this disease and to inform them about the various options for management and long-term outcome optimisation. There is currently conflicting data; however, institutional experiences can guide us towards achieving improvements in surgical outcomes and quality of life. Advances in molecular classifications coupled with highdose radiation treatment improve our capacity for improving overall survival in these patients. Common childhood tumours are ependymomas, medulloblastomas, and juvenile pilocytic astrocytomas, while adults often present with metastases, and less commonly, cerebellar haemangioblastomas and gliomas. This paper outlines management strategies with consideration for multidisciplinary care and resourcelimited settings.

Original languageEnglish
Pages (from-to)S186-S190
JournalJPMA. The Journal of the Pakistan Medical Association
Volume74
Issue number3 3
DOIs
Publication statusPublished - 1 Mar 2024

Keywords

  • Cerebellar neoplasms, medulloblastoma, caregivers, hemangioblastoma, astrocytoma, ependymoma, hydrocephalus, neuro-oncology, neurosurgery, brain tumour, posterior fossa.

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