TY - JOUR
T1 - Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries
AU - Pakistan Brain Tumour Consortium
AU - Aziz, Hafiza Fatima
AU - Bajwa, Mohammad Hamza
AU - Mushtaq, Naureen
AU - Bakhshi, Saqib Kamran
AU - Siddiqui, Kaynat
AU - Khan, Saad Akhtar
AU - Shakir, Muhammad
AU - Masroor, Mehar
AU - Suleman, Fatima
AU - Enam, Syed Ather
PY - 2024/3/1
Y1 - 2024/3/1
N2 - The posterior fossa is a limited compartment therefore lesions compressing its structures can result in devastating outcomes. It can cause significant neurological deficit due to mass effect on critical structures and hydrocephalus. Due to the nature of the infratentorial region, urgent surgical intervention is often the first-line option. Surgical neuro-oncologists guide patients and caregivers through the course of this disease and to inform them about the various options for management and long-term outcome optimisation. There is currently conflicting data; however, institutional experiences can guide us towards achieving improvements in surgical outcomes and quality of life. Advances in molecular classifications coupled with highdose radiation treatment improve our capacity for improving overall survival in these patients. Common childhood tumours are ependymomas, medulloblastomas, and juvenile pilocytic astrocytomas, while adults often present with metastases, and less commonly, cerebellar haemangioblastomas and gliomas. This paper outlines management strategies with consideration for multidisciplinary care and resourcelimited settings.
AB - The posterior fossa is a limited compartment therefore lesions compressing its structures can result in devastating outcomes. It can cause significant neurological deficit due to mass effect on critical structures and hydrocephalus. Due to the nature of the infratentorial region, urgent surgical intervention is often the first-line option. Surgical neuro-oncologists guide patients and caregivers through the course of this disease and to inform them about the various options for management and long-term outcome optimisation. There is currently conflicting data; however, institutional experiences can guide us towards achieving improvements in surgical outcomes and quality of life. Advances in molecular classifications coupled with highdose radiation treatment improve our capacity for improving overall survival in these patients. Common childhood tumours are ependymomas, medulloblastomas, and juvenile pilocytic astrocytomas, while adults often present with metastases, and less commonly, cerebellar haemangioblastomas and gliomas. This paper outlines management strategies with consideration for multidisciplinary care and resourcelimited settings.
KW - Cerebellar neoplasms, medulloblastoma, caregivers, hemangioblastoma, astrocytoma, ependymoma, hydrocephalus, neuro-oncology, neurosurgery, brain tumour, posterior fossa.
UR - http://www.scopus.com/inward/record.url?scp=85204041206&partnerID=8YFLogxK
U2 - 10.47391/JPMA.S3.GNO-22
DO - 10.47391/JPMA.S3.GNO-22
M3 - Article
C2 - 39262080
AN - SCOPUS:85204041206
SN - 0030-9982
VL - 74
SP - S186-S190
JO - JPMA. The Journal of the Pakistan Medical Association
JF - JPMA. The Journal of the Pakistan Medical Association
IS - 3 3
ER -