TY - JOUR
T1 - Consensus guidelines for the management of primary central nervous system lymphoma for low and middle-income countries
AU - Pakistan Brain Tumour Consortium
AU - Aziz, Hafiza Fatima
AU - Bakhshi, Saqib Kamran
AU - Ahmed, Noman
AU - Bajwa, Mohammad Hamza
AU - Jabbar, Adnan Abdul
AU - Hafiz, Asim
AU - Gilani, Ahmed
AU - Khalid, Muhammad Usman
AU - Enam, Syed Ather
PY - 2024/3/1
Y1 - 2024/3/1
N2 - Primary lymphoma of the central nervous system (PCNSL) is a rare and aggressive form of extranodal non-Hodgkin lymphoma primarily involving the brain, spinal cord, cerebrospinal fluid, and eyes. The role of surgical intervention in PCNSL is currently limited to biopsy and decompression of critical structures if needed - extended resection is debated. Chemotherapy is the mainstay of treatment. In lower and middle-income countries (LMICs), issues like delayed diagnosis and resource constraints are widespread. These guidelines provide a framework for addressing PCNSL in LMICs, emphasizing the importance of early diagnosis, tailored treatment approaches, and ongoing patient monitoring to improve outcomes for this rare and aggressive disease.
AB - Primary lymphoma of the central nervous system (PCNSL) is a rare and aggressive form of extranodal non-Hodgkin lymphoma primarily involving the brain, spinal cord, cerebrospinal fluid, and eyes. The role of surgical intervention in PCNSL is currently limited to biopsy and decompression of critical structures if needed - extended resection is debated. Chemotherapy is the mainstay of treatment. In lower and middle-income countries (LMICs), issues like delayed diagnosis and resource constraints are widespread. These guidelines provide a framework for addressing PCNSL in LMICs, emphasizing the importance of early diagnosis, tailored treatment approaches, and ongoing patient monitoring to improve outcomes for this rare and aggressive disease.
KW - Lymphoma, non-Hodgkin, biopsy, nervous system, physiologic decompression, spinal cord, brain tumours
UR - http://www.scopus.com/inward/record.url?scp=85204068663&partnerID=8YFLogxK
U2 - 10.47391/JPMA.S3.GNO-20
DO - 10.47391/JPMA.S3.GNO-20
M3 - Article
C2 - 39262078
AN - SCOPUS:85204068663
SN - 0030-9982
VL - 74
SP - S168-S176
JO - JPMA. The Journal of the Pakistan Medical Association
JF - JPMA. The Journal of the Pakistan Medical Association
IS - 3 3
ER -