TY - JOUR
T1 - Controversies about radioactive iodine-131 remnant ablation in low risk thyroid cancers
T2 - Are we near a consensus?
AU - Uz Zaman, Maseeh
AU - Fatima, Nosheen
AU - Padhy, Ajit Kumar
AU - Zaman, Unaiza
PY - 2013
Y1 - 2013
N2 - Well differentiated thyroid cancers (WDTC), including papillary (80%) and follicular (10%) types, are the most common endocrine cancers globally. Over the last few decades most the diagnosed cases have fallen into low risk categories. Radioactive iodine-131 (RAI) has an established role in reducing recurrence and improving the survival in high risk patients. In patients with primary tumor size <1 cm, RAI is not recommended by many thyroid societies. However, low risk WDTC has been an arena of major controversies, most importantly the role and dose of adjuvant RAI for remnant ablation to minimize chances of recurrence and improving survival. This review is an attempt to update readers about the previous and existing practice based on results of nonrandomized trials and evolving trends fueled by recently published randomized studies.
AB - Well differentiated thyroid cancers (WDTC), including papillary (80%) and follicular (10%) types, are the most common endocrine cancers globally. Over the last few decades most the diagnosed cases have fallen into low risk categories. Radioactive iodine-131 (RAI) has an established role in reducing recurrence and improving the survival in high risk patients. In patients with primary tumor size <1 cm, RAI is not recommended by many thyroid societies. However, low risk WDTC has been an arena of major controversies, most importantly the role and dose of adjuvant RAI for remnant ablation to minimize chances of recurrence and improving survival. This review is an attempt to update readers about the previous and existing practice based on results of nonrandomized trials and evolving trends fueled by recently published randomized studies.
KW - Follicular thyroid cancer
KW - Low dose iodine
KW - Papillary thyroid cancer
KW - Remnant ablation
UR - http://www.scopus.com/inward/record.url?scp=84892462312&partnerID=8YFLogxK
U2 - 10.7314/APJCP.2013.14.11.6209
DO - 10.7314/APJCP.2013.14.11.6209
M3 - Short survey
C2 - 24377506
AN - SCOPUS:84892462312
SN - 1513-7368
VL - 14
SP - 6209
EP - 6213
JO - Asian Pacific Journal of Cancer Prevention
JF - Asian Pacific Journal of Cancer Prevention
IS - 11
ER -
