Coronary calcium scoring: Are the results comparable to computed tomography coronary angiography for screening coronary artery disease in a South Asian population?

Nizar Bhulani, Ali Khawaja, Asif Jafferani, Maryam Baqir, Ramin Ebrahimi, Zafar Sajjad

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Background: The need of having feasible screening tools like Coronary Calcium Scoring (CCS) and CT Coronary Artery (CTCA) for Coronary Artery Disease (CAD) has become paramount. We aimed to evaluate the accuracy of CCS in determining the degree of stenosis of coronary vessels as compared to that determined by CTCA in a South Asian population. Methods. A retrospective study was conducted at The Aga Khan University Hospital. A total of 539 patient records were reviewed who had undergone CCS and CTCA between 2008 and 2010. Patient records were reviewed by comparing their CCS and CTCA results. Results: About 268 out of 301 (89%) patients with a CCS of 0-9 were found to be free of stenosis on CTCA. On a CCS of 10-99, 110 out of 121 (91%) patients were either free of stenosis or had mild stenosis. About 66 out of 79 (84%) patients had moderate or severe stenosis with a calcium score of 100-400 while none of the patients were free of stenosis. Around 28 out of 38 (74%) patients with a CCS of more than 400 had severe stenosis. However, only 04 patients (11%) were found to have mild stenosis. Spearman's rho revealed a correlation coefficient of 0.791 with a p-value of <0.001. Conclusion: Our study reaffirms that in South Asian population, low CCS (<100) is associated with no or minimal stenosis while high CCS warrants further investigation; hence, making it a reliable tool for screening patients with CAD.

Original languageEnglish
Article number279
JournalBMC Research Notes
Volume6
Issue number1
DOIs
Publication statusPublished - 2013

Keywords

  • CT Coronary artery
  • Coronary artery disease
  • Coronary calcium scoring
  • Pakistan
  • South Asia
  • Stenosis

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