Correlation between laparoscopic and histopathologic diagnosis of endometriosis

Sikolia Z. Wanyonyi, Evan Sequeira, Samuel G. Mukono

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Objective: To review the histopathologic diagnosis of biopsies taken following visualization of endometriosis at laparoscopy and to correlate visual with microscopic diagnoses. Methods: A retrospective review was undertaken of medical charts with a diagnosis of endometriosis at Aga Khan University Hospital, Nairobi, Kenya, between January 2001 and October 2010. Eligibility included visual diagnosis of endometriosis at laparoscopy, with a clear record of site, size, morphology, and number of lesions. The histopathologic diagnosis of the biopsies sampled was sought. Correlation was undertaken using κ statistics for diagnostic variability. Results: Of the 204 relevant records, 152 (74.5%) met the eligibility criteria; from these cases, 239 specimens were submitted for histology. The most common symptom was chronic pelvic pain (108 [71.1%]). Most biopsies were obtained from the ovary and posterior cul-de-sac. Histopathologic diagnosis was confirmed in (152 [63.8%]) specimens and correlated with Asian race, multiparity, and chronic pelvic pain. Neither the site of the lesion nor the stage of disease influenced the histopathologic diagnosis. Conclusion: Laparoscopic visualization of endometriosis does not always correlate with histopathologic diagnosis; several other lesions may mimic endometriosis on histopathologic examination.

Original languageEnglish
Pages (from-to)273-276
Number of pages4
JournalInternational Journal of Gynecology and Obstetrics
Issue number3
Publication statusPublished - Dec 2011


  • Diagnosis
  • Endometriosis
  • Histology
  • Histopathology
  • Laparoscopy


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