TY - JOUR
T1 - Cutaneous Manifestations of Systemic Lupus Erythematosus in Pakistani Patients
AU - Rabbani, M. A.
AU - Shah, S. M.A.
AU - Ahmed, A.
PY - 2003/11
Y1 - 2003/11
N2 - Objective: Systemic Lupus Erythematosus (SLE) is an autoimmune process in which cutaneous lesions occur in majority of patients. This study from Karachi, Pakistan was conducted to determine the pattern and prevalence of such lesions in SLE in Pakistani patients. Methods: One hundred ninety eight patients with SLE fulfilling the clinical and laboratory criteria of the American Rheumatology Association were examined between 1986 and 2001 for the presence of cutaneous manifestations. Results: Skin changes noted were: noncicatricial diffuse alopecia (22%), malar rash (31%), mucosal lesions (20%), discoid eruptions (15%), photosensitivity (33%), vascular lesions (20%), pruritis (17%), and pigmentary changes (22%). Peripheral gangrene, chronic ulcers, Raynauds phenomenon, urticaria, chilblains, thrombophlebitis, palmar erythema, and erythema multiform were rare. Anti ANA and anti dsDNA were positive in 93% and 83% patients respectively. Conclusion: A different clinical pattern was noted in our patients than reported previously.
AB - Objective: Systemic Lupus Erythematosus (SLE) is an autoimmune process in which cutaneous lesions occur in majority of patients. This study from Karachi, Pakistan was conducted to determine the pattern and prevalence of such lesions in SLE in Pakistani patients. Methods: One hundred ninety eight patients with SLE fulfilling the clinical and laboratory criteria of the American Rheumatology Association were examined between 1986 and 2001 for the presence of cutaneous manifestations. Results: Skin changes noted were: noncicatricial diffuse alopecia (22%), malar rash (31%), mucosal lesions (20%), discoid eruptions (15%), photosensitivity (33%), vascular lesions (20%), pruritis (17%), and pigmentary changes (22%). Peripheral gangrene, chronic ulcers, Raynauds phenomenon, urticaria, chilblains, thrombophlebitis, palmar erythema, and erythema multiform were rare. Anti ANA and anti dsDNA were positive in 93% and 83% patients respectively. Conclusion: A different clinical pattern was noted in our patients than reported previously.
UR - https://www.scopus.com/pages/publications/0346458983
M3 - Article
C2 - 14738261
AN - SCOPUS:0346458983
SN - 0030-9982
VL - 53
SP - 539
EP - 541
JO - Journal of the Pakistan Medical Association
JF - Journal of the Pakistan Medical Association
IS - 11
ER -