Dermatofibrosarcoma protuberans of the breast

Muskaan Qadir, Saira Fatima, Safdar Shaikh, Sana Zeeshan

Research output: Contribution to journalArticlepeer-review


Dermatofibrosarcoma protuberans (DFSP) of the breast is an infrequent soft tissue sarcoma that usually affects young to middle-aged women. Our case report describes a unique occurrence of DFSP of the breast in an adolescent girl, which was initially being managed as a keloid for 2 years under dermatology despite being refractory to treatment. Once the diagnosis of DFSP was confirmed through punch biopsy, our patient underwent surgical excision of the lesion under general anaesthesia. Our patient was at an increased risk of damage to the ductal system due to proximity of the lesion to the nipple-areolar complex, warranting the need for early recognition and treatment. As demonstrated by our case, DFSP of the breast can be difficult to diagnose since it resembles a range of benign and malignant pathologies of the breast.

Original languageEnglish
JournalBMJ Case Reports
Issue number4
Publication statusPublished - 11 Apr 2024


  • Breast surgery
  • Pathology
  • Plastic and reconstructive surgery
  • Skin cancer


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