Detection of metallo-β-lactamase producing clinical gram-negative non-fermenting isolates

Darakhshan Guhar; Seema Irfan; Afia Zafar; Tanveer Ahsan; Rumina Hasan

doi:10.1109/IBCAST.2014.6778124

Detection of metallo-β-lactamase producing clinical gram-negative non-fermenting isolates

Darakhshan Guhar, Seema Irfan, Afia Zafar, Tanveer Ahsan, Rumina Hasan

Research output: Contribution to conference › Paper › peer-review

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Abstract

There is a remarkable increase in antibiotic resistance due to metallo-β-lactamase-production among gram-negative non-fermenting organisms. Early detection of metallo-β-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Imipenem-EDTA disk method was used for the detection of MBL producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa. One hundred MDR Acinetobacter spp. and forty-two Pseudomonas aeruginosa were screened for MBL production, from January to June 2001. MBL was produced by 96.6 % of imipenem-resistant Acinetobacter isolates, whereas 100% imipenem-resistant Pseudomonas aeroginosa isolates were MBL producers. MBLs are responsible for carbapenem resistance in these MDR Acinetobacter spp. and Pseudomonas aeruginosa There is an urgent need to have a simple screening test to take infection control measures on time.

Original language	English (UK)
Pages	73-74
Number of pages	2
DOIs	https://doi.org/10.1109/IBCAST.2014.6778124
Publication status	Published - 2014
Event	2014 11th International Bhurban Conference on Applied Sciences and Technology, IBCAST 2014 - Islamabad, Pakistan Duration: 14 Jan 2014 → 18 Jan 2014

Conference

Conference	2014 11th International Bhurban Conference on Applied Sciences and Technology, IBCAST 2014
Country/Territory	Pakistan
City	Islamabad
Period	14/01/14 → 18/01/14

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10.1109/IBCAST.2014.6778124

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title = "Detection of metallo-β-lactamase producing clinical gram-negative non-fermenting isolates",

abstract = "There is a remarkable increase in antibiotic resistance due to metallo-β-lactamase-production among gram-negative non-fermenting organisms. Early detection of metallo-β-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Imipenem-EDTA disk method was used for the detection of MBL producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa. One hundred MDR Acinetobacter spp. and forty-two Pseudomonas aeruginosa were screened for MBL production, from January to June 2001. MBL was produced by 96.6 \% of imipenem-resistant Acinetobacter isolates, whereas 100\% imipenem-resistant Pseudomonas aeroginosa isolates were MBL producers. MBLs are responsible for carbapenem resistance in these MDR Acinetobacter spp. and Pseudomonas aeruginosa There is an urgent need to have a simple screening test to take infection control measures on time.",

author = "Darakhshan Guhar and Seema Irfan and Afia Zafar and Tanveer Ahsan and Rumina Hasan",

year = "2014",

doi = "10.1109/IBCAST.2014.6778124",

language = "English (UK)",

pages = "73--74",

note = "2014 11th International Bhurban Conference on Applied Sciences and Technology, IBCAST 2014 ; Conference date: 14-01-2014 Through 18-01-2014",

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AU - Guhar, Darakhshan

AU - Irfan, Seema

AU - Zafar, Afia

AU - Ahsan, Tanveer

AU - Hasan, Rumina

PY - 2014

Y1 - 2014

N2 - There is a remarkable increase in antibiotic resistance due to metallo-β-lactamase-production among gram-negative non-fermenting organisms. Early detection of metallo-β-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Imipenem-EDTA disk method was used for the detection of MBL producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa. One hundred MDR Acinetobacter spp. and forty-two Pseudomonas aeruginosa were screened for MBL production, from January to June 2001. MBL was produced by 96.6 % of imipenem-resistant Acinetobacter isolates, whereas 100% imipenem-resistant Pseudomonas aeroginosa isolates were MBL producers. MBLs are responsible for carbapenem resistance in these MDR Acinetobacter spp. and Pseudomonas aeruginosa There is an urgent need to have a simple screening test to take infection control measures on time.

AB - There is a remarkable increase in antibiotic resistance due to metallo-β-lactamase-production among gram-negative non-fermenting organisms. Early detection of metallo-β-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Imipenem-EDTA disk method was used for the detection of MBL producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa. One hundred MDR Acinetobacter spp. and forty-two Pseudomonas aeruginosa were screened for MBL production, from January to June 2001. MBL was produced by 96.6 % of imipenem-resistant Acinetobacter isolates, whereas 100% imipenem-resistant Pseudomonas aeroginosa isolates were MBL producers. MBLs are responsible for carbapenem resistance in these MDR Acinetobacter spp. and Pseudomonas aeruginosa There is an urgent need to have a simple screening test to take infection control measures on time.

UR - https://www.scopus.com/pages/publications/84899027816

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DO - 10.1109/IBCAST.2014.6778124

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T2 - 2014 11th International Bhurban Conference on Applied Sciences and Technology, IBCAST 2014

Y2 - 14 January 2014 through 18 January 2014

ER -

Detection of metallo-β-lactamase producing clinical gram-negative non-fermenting isolates

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