Detection of NDM-1-producing Klebsiella pneumoniae in Kenya

Laurent Poirel, Gunturu Revathi, Sandrine Bernabeu, Patrice Nordmann

Research output: Contribution to journalArticlepeer-review

174 Citations (Scopus)

Abstract

Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla NDM-1 carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

Original languageEnglish
Pages (from-to)934-936
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume55
Issue number2
DOIs
Publication statusPublished - Feb 2011

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