Detection of NDM-1-producing Klebsiella pneumoniae in Kenya

Laurent Poirel; Gunturu Revathi; Sandrine Bernabeu; Patrice Nordmann

doi:10.1128/AAC.01247-10

Detection of NDM-1-producing Klebsiella pneumoniae in Kenya

Laurent Poirel
, Gunturu Revathi
, Sandrine Bernabeu
, Patrice Nordmann

Research output: Contribution to journal › Article › peer-review

181 Citations (Scopus)

Abstract

Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla _NDM-1 carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

Original language	English (US)
Pages (from-to)	934-936
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	55
Issue number	2
DOIs	https://doi.org/10.1128/AAC.01247-10
Publication status	Published - Feb 2011
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1128/AAC.01247-10

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abstract = "Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla NDM-1 carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.",

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AU - Poirel, Laurent

AU - Revathi, Gunturu

AU - Bernabeu, Sandrine

AU - Nordmann, Patrice

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Y1 - 2011/2

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AB - Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla NDM-1 carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

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JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 2

ER -

Detection of NDM-1-producing Klebsiella pneumoniae in Kenya

Abstract

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