TY - JOUR
T1 - Diffuse large B cell lymphoma (DLBCL) in pakistan
T2 - An emerging epidemic?
AU - Abid, Muhammad Bilal
AU - Nasim, Faria
AU - Anwar, Kashif
AU - Pervez, Shahid
PY - 2005
Y1 - 2005
N2 - There has been a recent concern among oncological clinicians and pathologists of our region regarding the disproportionate increase in the number of patients presenting with diffuse large B cell lymphoma (DLBCL). This prompted us to conduct a thorough, hospital-based epidemiological study in a major referral center of Pakistan. A total of 780 specimens were collected over last half decade from cases classified as adult Non Hodgkin's lymphoma (NHL). Out of these 780, 596 (76.4 %)were diagnosed as DLBCLs. The gender ratio was 2.3: 1 (M: F) and the median age was 47.2 years, with an age range of 15-85years. Nodal-NHLs constituted 42.2 % of all adult NHLs, with the cervical lymph nodes as the most frequent nodal site of presentation. The most frequent extranodal site was the gastro-intestinal tract (GIT), followed by the head and neck. In conclusion, we document an astonishingly high number of DLBCL amounting to an emerging epidemic in Pakistan, with a consideration of probable etiopathogenetic factors.
AB - There has been a recent concern among oncological clinicians and pathologists of our region regarding the disproportionate increase in the number of patients presenting with diffuse large B cell lymphoma (DLBCL). This prompted us to conduct a thorough, hospital-based epidemiological study in a major referral center of Pakistan. A total of 780 specimens were collected over last half decade from cases classified as adult Non Hodgkin's lymphoma (NHL). Out of these 780, 596 (76.4 %)were diagnosed as DLBCLs. The gender ratio was 2.3: 1 (M: F) and the median age was 47.2 years, with an age range of 15-85years. Nodal-NHLs constituted 42.2 % of all adult NHLs, with the cervical lymph nodes as the most frequent nodal site of presentation. The most frequent extranodal site was the gastro-intestinal tract (GIT), followed by the head and neck. In conclusion, we document an astonishingly high number of DLBCL amounting to an emerging epidemic in Pakistan, with a consideration of probable etiopathogenetic factors.
KW - DLBCL
KW - NHL
KW - Pakistani adults
UR - http://www.scopus.com/inward/record.url?scp=33646701944&partnerID=8YFLogxK
M3 - Article
C2 - 16436006
AN - SCOPUS:33646701944
SN - 1513-7368
VL - 6
SP - 531
EP - 534
JO - Asian Pacific Journal of Cancer Prevention
JF - Asian Pacific Journal of Cancer Prevention
IS - 4
ER -
