Disseminated histoplasmosis

Akshat Banga; Riecha Joshi; Rahul Kashyap; Reena Shah; Salim Surani

Disseminated histoplasmosis

Akshat Banga, Riecha Joshi, Rahul Kashyap, Reena Shah, Salim Surani

Medical College, East Africa

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, a facultative intracellular parasite of the system. It is predominantly found in North America, primarily Midwestern and Southeastern United States. Transmitted by inhalation of airborne fungal conidia, H. capsulatum can cause mild to severe respiratory illness. Dissemination of histoplasmosis occurs in immunocompromised patients following initial infection, reinfection, or reactivation of the latent foci. Histoplasma initially disseminates to organs rich in reticuloendothelial cells, but it can infect any organ/organ system, including central nervous system (CNS), gastrointestinal tract (GIT), skin, and adrenal glands, etc. Disseminated histoplasmosis is considered one of the acquired immunodeficiency syndrome (AIDS)-defining infections, and it usually occurs in HIV-infected individuals with a CD4 count<200/mm³.

Original language	English
Title of host publication	Histoplasmosis
Subtitle of host publication	From Diagnosis to Treatment
Publisher	Nova Science Publishers, Inc.
Pages	231-267
Number of pages	37
ISBN (Electronic)	9798891132283
ISBN (Print)	9798891131293
Publication status	Published - 27 Nov 2023

Keywords

AIDS
CNS histoplasmosis
Disseminated histoplasmosis
GI histoplasmosis
Histoplasmosis
Immunocompromised
TNF-alpha

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, a facultative intracellular parasite of the system. It is predominantly found in North America, primarily Midwestern and Southeastern United States. Transmitted by inhalation of airborne fungal conidia, H. capsulatum can cause mild to severe respiratory illness. Dissemination of histoplasmosis occurs in immunocompromised patients following initial infection, reinfection, or reactivation of the latent foci. Histoplasma initially disseminates to organs rich in reticuloendothelial cells, but it can infect any organ/organ system, including central nervous system (CNS), gastrointestinal tract (GIT), skin, and adrenal glands, etc. Disseminated histoplasmosis is considered one of the acquired immunodeficiency syndrome (AIDS)-defining infections, and it usually occurs in HIV-infected individuals with a CD4 count<200/mm3.",

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TY - CHAP

T1 - Disseminated histoplasmosis

AU - Banga, Akshat

AU - Joshi, Riecha

AU - Kashyap, Rahul

AU - Shah, Reena

AU - Surani, Salim

PY - 2023/11/27

Y1 - 2023/11/27

N2 - Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, a facultative intracellular parasite of the system. It is predominantly found in North America, primarily Midwestern and Southeastern United States. Transmitted by inhalation of airborne fungal conidia, H. capsulatum can cause mild to severe respiratory illness. Dissemination of histoplasmosis occurs in immunocompromised patients following initial infection, reinfection, or reactivation of the latent foci. Histoplasma initially disseminates to organs rich in reticuloendothelial cells, but it can infect any organ/organ system, including central nervous system (CNS), gastrointestinal tract (GIT), skin, and adrenal glands, etc. Disseminated histoplasmosis is considered one of the acquired immunodeficiency syndrome (AIDS)-defining infections, and it usually occurs in HIV-infected individuals with a CD4 count<200/mm3.

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KW - AIDS

KW - CNS histoplasmosis

KW - Disseminated histoplasmosis

KW - GI histoplasmosis

KW - Histoplasmosis

KW - Immunocompromised

KW - TNF-alpha

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M3 - Chapter

AN - SCOPUS:85180683749

SN - 9798891131293

SP - 231

EP - 267

BT - Histoplasmosis

PB - Nova Science Publishers, Inc.

ER -

Disseminated histoplasmosis

Abstract

Keywords

UN SDGs

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