Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

Jalil ur Rehman; J. Ashraf; Muhammad Isa; Muhammad Afzal; G. Ibbott; James Chow

doi:10.1007/978-3-319-19387-8_154

Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

Jalil ur Rehman
, J. Ashraf
, Muhammad Isa
, Muhammad Afzal
, G. Ibbott
, James Chow

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.

Original language	English (UK)
Title of host publication	World Congress on Medical Physics and Biomedical Engineering, 2015
Editors	David A. Jaffray
Publisher	Springer Verlag
Pages	633-636
Number of pages	4
ISBN (Print)	9783319193878
DOIs	https://doi.org/10.1007/978-3-319-19387-8_154
Publication status	Published - 2015
Externally published	Yes
Event	World Congress on Medical Physics and Biomedical Engineering, 2015 - Toronto, Canada Duration: 7 Jun 2015 → 12 Jun 2015

Publication series

Name	IFMBE Proceedings
Volume	51
ISSN (Print)	1680-0737

Conference

Conference	World Congress on Medical Physics and Biomedical Engineering, 2015
Country/Territory	Canada
City	Toronto
Period	7/06/15 → 12/06/15

Keywords

3DCRT
IMRT
Second cancer risk
Spine radiotherapy
VMAT

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/978-3-319-19387-8_154

Cite this

ur Rehman, J., Ashraf, J., Isa, M., Afzal, M., Ibbott, G., & Chow, J. (2015). Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk. In D. A. Jaffray (Ed.), World Congress on Medical Physics and Biomedical Engineering, 2015 (pp. 633-636). (IFMBE Proceedings; Vol. 51). Springer Verlag. https://doi.org/10.1007/978-3-319-19387-8_154

@inproceedings{c7f914a5b6a541949f93f09b63500107,

title = "Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk",

abstract = "This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3\%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5\%, 91.4\% and 95.9\%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0\% for VMAT, 37.56\% for IMRT and up to 43.76\% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.",

keywords = "3DCRT, IMRT, Second cancer risk, Spine radiotherapy, VMAT",

author = "\{ur Rehman\}, Jalil and J. Ashraf and Muhammad Isa and Muhammad Afzal and G. Ibbott and James Chow",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.; World Congress on Medical Physics and Biomedical Engineering, 2015 ; Conference date: 07-06-2015 Through 12-06-2015",

year = "2015",

doi = "10.1007/978-3-319-19387-8\_154",

language = "English (UK)",

isbn = "9783319193878",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

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ur Rehman, J, Ashraf, J, Isa, M, Afzal, M, Ibbott, G & Chow, J 2015, Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk. in DA Jaffray (ed.), World Congress on Medical Physics and Biomedical Engineering, 2015. IFMBE Proceedings, vol. 51, Springer Verlag, pp. 633-636, World Congress on Medical Physics and Biomedical Engineering, 2015, Toronto, Canada, 7/06/15. https://doi.org/10.1007/978-3-319-19387-8_154

Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk. / ur Rehman, Jalil; Ashraf, J.; Isa, Muhammad et al.
World Congress on Medical Physics and Biomedical Engineering, 2015. ed. / David A. Jaffray. Springer Verlag, 2015. p. 633-636 (IFMBE Proceedings; Vol. 51).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

AU - ur Rehman, Jalil

AU - Ashraf, J.

AU - Isa, Muhammad

AU - Afzal, Muhammad

AU - Ibbott, G.

AU - Chow, James

N1 - Publisher Copyright: © Springer International Publishing Switzerland 2015.

PY - 2015

Y1 - 2015

N2 - This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.

AB - This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.

KW - 3DCRT

KW - IMRT

KW - Second cancer risk

KW - Spine radiotherapy

KW - VMAT

UR - https://www.scopus.com/pages/publications/84944322890

U2 - 10.1007/978-3-319-19387-8_154

DO - 10.1007/978-3-319-19387-8_154

M3 - Conference contribution

AN - SCOPUS:84944322890

SN - 9783319193878

T3 - IFMBE Proceedings

SP - 633

EP - 636

BT - World Congress on Medical Physics and Biomedical Engineering, 2015

A2 - Jaffray, David A.

PB - Springer Verlag

T2 - World Congress on Medical Physics and Biomedical Engineering, 2015

Y2 - 7 June 2015 through 12 June 2015

ER -

Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

Abstract

Publication series

Conference

Keywords

UN SDGs

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