Effect of anti-mycobacterial antibodies on activation of the alternative pathway of the human complement system

Om Parkash; V. D. Ramanathan; D. P. Singh; U. Sengupta

doi:10.1111/j.1574-6968.1988.tb02810.x

Effect of anti-mycobacterial antibodies on activation of the alternative pathway of the human complement system

Om Parkash, V. D. Ramanathan, D. P. Singh, U. Sengupta

Department of Medicine, Medical College, Pakistan

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Mycobacterium vaccae and BCG showed activation (at the level of C3) of the alternative pathway of the human complement system as seen by enzyme linked immunosorbent assay (ELISA). Antimycobacterial antibodies were found to have enhancing effect on C3 uptake by these mycobacteria. The homologous antibodies showed more enhancing effect in comparison to heterologous antibodies.

Original language	English (US)
Pages (from-to)	255-258
Number of pages	4
Journal	FEMS Microbiology Letters
Volume	55
Issue number	3
DOIs	https://doi.org/10.1111/j.1574-6968.1988.tb02810.x
Publication status	Published - 15 Oct 1988

Keywords

Antibody
BCG
Complement
Mycobacteria

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10.1111/j.1574-6968.1988.tb02810.x

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abstract = "Mycobacterium vaccae and BCG showed activation (at the level of C3) of the alternative pathway of the human complement system as seen by enzyme linked immunosorbent assay (ELISA). Antimycobacterial antibodies were found to have enhancing effect on C3 uptake by these mycobacteria. The homologous antibodies showed more enhancing effect in comparison to heterologous antibodies.",

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AU - Ramanathan, V. D.

AU - Singh, D. P.

AU - Sengupta, U.

PY - 1988/10/15

Y1 - 1988/10/15

N2 - Mycobacterium vaccae and BCG showed activation (at the level of C3) of the alternative pathway of the human complement system as seen by enzyme linked immunosorbent assay (ELISA). Antimycobacterial antibodies were found to have enhancing effect on C3 uptake by these mycobacteria. The homologous antibodies showed more enhancing effect in comparison to heterologous antibodies.

AB - Mycobacterium vaccae and BCG showed activation (at the level of C3) of the alternative pathway of the human complement system as seen by enzyme linked immunosorbent assay (ELISA). Antimycobacterial antibodies were found to have enhancing effect on C3 uptake by these mycobacteria. The homologous antibodies showed more enhancing effect in comparison to heterologous antibodies.

KW - Antibody

KW - BCG

KW - Complement

KW - Mycobacteria

UR - https://www.scopus.com/pages/publications/0023739071

U2 - 10.1111/j.1574-6968.1988.tb02810.x

DO - 10.1111/j.1574-6968.1988.tb02810.x

M3 - Article

AN - SCOPUS:0023739071

SN - 0378-1097

VL - 55

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JO - FEMS Microbiology Letters

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ER -

Effect of anti-mycobacterial antibodies on activation of the alternative pathway of the human complement system

Abstract

Keywords

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