Effects of dietary copper exposure on accumulation, growth, and hematological parameters in Cyprinus carpio

A. S. Al-Akel; H. F.Alkahem Al-Balawi; F. Al-Misned; Shahid Mahboobab; Z. Ahmad; E. M. Suliman

doi:10.1080/02772248.2010.486230

Effects of dietary copper exposure on accumulation, growth, and hematological parameters in Cyprinus carpio

A. S. Al-Akel, H. F.Alkahem Al-Balawi, F. Al-Misned, Shahid Mahboobab, Z. Ahmad, E. M. Suliman

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The influence of dietary copper (Cu) exposure on accumulation, growth, and hematological parameters was investigated in Cyprinus carpio after sub-chronic ingestion of 0, 250, 500, 750 or 1000mg kg^-1 for 60 days. The profile of Cu accumulation among tissues in C. carpio was dependent on the exposure period and Cu concentration. Liver of C. carpio was the predominant storage tissue and the order of Cu accumulation in tissues was liver>intestine> gill>kidney>muscle. Cu concentration at 4125mg kg^-1 reduced growth rate, and was inversely related to growth. The RNA:DNA ratios were not affected by exposure and there was no correlation between growth rate and RNA:DNA ratio in liver and muscle. There were no significant effects of exposure on blood parameters except for magnesium. Cu exposure time and dose increased the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) activity levels.

Original language	English
Pages (from-to)	1865-1878
Number of pages	14
Journal	Toxicological and Environmental Chemistry
Volume	92
Issue number	10
DOIs	https://doi.org/10.1080/02772248.2010.486230
Publication status	Published - 2010
Externally published	Yes

Keywords

Cprinus carpio
Dietary copper
Growth
Hematological parameters
Rna:dna ratio

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10.1080/02772248.2010.486230

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title = "Effects of dietary copper exposure on accumulation, growth, and hematological parameters in Cyprinus carpio",

abstract = "The influence of dietary copper (Cu) exposure on accumulation, growth, and hematological parameters was investigated in Cyprinus carpio after sub-chronic ingestion of 0, 250, 500, 750 or 1000mg kg-1 for 60 days. The profile of Cu accumulation among tissues in C. carpio was dependent on the exposure period and Cu concentration. Liver of C. carpio was the predominant storage tissue and the order of Cu accumulation in tissues was liver>intestine> gill>kidney>muscle. Cu concentration at 4125mg kg-1 reduced growth rate, and was inversely related to growth. The RNA:DNA ratios were not affected by exposure and there was no correlation between growth rate and RNA:DNA ratio in liver and muscle. There were no significant effects of exposure on blood parameters except for magnesium. Cu exposure time and dose increased the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) activity levels.",

keywords = "Cprinus carpio, Dietary copper, Growth, Hematological parameters, Rna:dna ratio",

author = "Al-Akel, {A. S.} and Al-Balawi, {H. F.Alkahem} and F. Al-Misned and Shahid Mahboobab and Z. Ahmad and Suliman, {E. M.}",

note = "Funding Information: The authors gratefully acknowledge Research Centre, College of Science, King Saud University, Kingdom of Saudi Arabia, for providing funding to carry out the research work.",

year = "2010",

doi = "10.1080/02772248.2010.486230",

language = "English",

volume = "92",

pages = "1865--1878",

journal = "Toxicological and Environmental Chemistry",

issn = "0277-2248",

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TY - JOUR

T1 - Effects of dietary copper exposure on accumulation, growth, and hematological parameters in Cyprinus carpio

AU - Al-Akel, A. S.

AU - Al-Balawi, H. F.Alkahem

AU - Al-Misned, F.

AU - Mahboobab, Shahid

AU - Ahmad, Z.

AU - Suliman, E. M.

N1 - Funding Information: The authors gratefully acknowledge Research Centre, College of Science, King Saud University, Kingdom of Saudi Arabia, for providing funding to carry out the research work.

PY - 2010

Y1 - 2010

N2 - The influence of dietary copper (Cu) exposure on accumulation, growth, and hematological parameters was investigated in Cyprinus carpio after sub-chronic ingestion of 0, 250, 500, 750 or 1000mg kg-1 for 60 days. The profile of Cu accumulation among tissues in C. carpio was dependent on the exposure period and Cu concentration. Liver of C. carpio was the predominant storage tissue and the order of Cu accumulation in tissues was liver>intestine> gill>kidney>muscle. Cu concentration at 4125mg kg-1 reduced growth rate, and was inversely related to growth. The RNA:DNA ratios were not affected by exposure and there was no correlation between growth rate and RNA:DNA ratio in liver and muscle. There were no significant effects of exposure on blood parameters except for magnesium. Cu exposure time and dose increased the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) activity levels.

AB - The influence of dietary copper (Cu) exposure on accumulation, growth, and hematological parameters was investigated in Cyprinus carpio after sub-chronic ingestion of 0, 250, 500, 750 or 1000mg kg-1 for 60 days. The profile of Cu accumulation among tissues in C. carpio was dependent on the exposure period and Cu concentration. Liver of C. carpio was the predominant storage tissue and the order of Cu accumulation in tissues was liver>intestine> gill>kidney>muscle. Cu concentration at 4125mg kg-1 reduced growth rate, and was inversely related to growth. The RNA:DNA ratios were not affected by exposure and there was no correlation between growth rate and RNA:DNA ratio in liver and muscle. There were no significant effects of exposure on blood parameters except for magnesium. Cu exposure time and dose increased the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) activity levels.

KW - Cprinus carpio

KW - Dietary copper

KW - Growth

KW - Hematological parameters

KW - Rna:dna ratio

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U2 - 10.1080/02772248.2010.486230

DO - 10.1080/02772248.2010.486230

M3 - Article

AN - SCOPUS:77958466474

SN - 0277-2248

VL - 92

SP - 1865

EP - 1878

JO - Toxicological and Environmental Chemistry

JF - Toxicological and Environmental Chemistry

IS - 10

ER -

Effects of dietary copper exposure on accumulation, growth, and hematological parameters in Cyprinus carpio

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Keywords

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