TY - JOUR
T1 - Effects of intravenous diclofenac on postoperative sore throat in patients undergoing laparoscopic surgery at Aga Khan University hospital, Nairobi
T2 - A prospective, randomized, double blind controlled trial
AU - Thang'a, P.
AU - Kamya, D.
AU - Mung'ayi, Vitalis
PY - 2013
Y1 - 2013
N2 - Background: postoperative sore throat is the commonest complication after endotracheal intubation. The efficacy of intravenous non-steroidal anti-inflammatory drugs in alleviating postoperative sore throat has not been investigated. Objective: To evaluate the effect of intravenous diclofenac sodium on the occurrence and severity of postoperative sore throat. Methods: 42 in-patients scheduled for laparoscopic surgery were randomized into two equal groups to receive either a single dose of 75mg intravenous diclofenac sodium in addition to standard treatment taken at our hospital for the prevention of postoperative sore throat or to receive standard treatment only. All patients were interviewed postoperatively at 2, 6 and 18 hours. Data of the baseline characteristics, the incidence and severity of sore throat were collected. If sore throat was present, a Visual Analogue Score was used to assess its severity. Results: the baseline characteristics of the participants were similar. The majority of the patients undergoing laparoscopic surgery were women. There was no statistically significant difference in the occurrence or severity of postoperative sore throat between the diclofenac and standard treatment groups at 2, 6 and 18 hours postoperatively. Conclusion: Intravenous diclofenac sodium does not reduce the occurrence or severity of postoperative sore throat.
AB - Background: postoperative sore throat is the commonest complication after endotracheal intubation. The efficacy of intravenous non-steroidal anti-inflammatory drugs in alleviating postoperative sore throat has not been investigated. Objective: To evaluate the effect of intravenous diclofenac sodium on the occurrence and severity of postoperative sore throat. Methods: 42 in-patients scheduled for laparoscopic surgery were randomized into two equal groups to receive either a single dose of 75mg intravenous diclofenac sodium in addition to standard treatment taken at our hospital for the prevention of postoperative sore throat or to receive standard treatment only. All patients were interviewed postoperatively at 2, 6 and 18 hours. Data of the baseline characteristics, the incidence and severity of sore throat were collected. If sore throat was present, a Visual Analogue Score was used to assess its severity. Results: the baseline characteristics of the participants were similar. The majority of the patients undergoing laparoscopic surgery were women. There was no statistically significant difference in the occurrence or severity of postoperative sore throat between the diclofenac and standard treatment groups at 2, 6 and 18 hours postoperatively. Conclusion: Intravenous diclofenac sodium does not reduce the occurrence or severity of postoperative sore throat.
UR - http://www.scopus.com/inward/record.url?scp=84893900995&partnerID=8YFLogxK
U2 - 10.4314/ahs.v13i4.20
DO - 10.4314/ahs.v13i4.20
M3 - Article
C2 - 24940324
AN - SCOPUS:84893900995
SN - 1680-6905
VL - 13
SP - 999
EP - 1006
JO - African Health Sciences
JF - African Health Sciences
IS - 4
ER -