Entamoeba species associated with chronic diarrhoea in Pakistan

J. Yakoob, Z. Abbas, M. A. Beg, S. Naz, R. Khan, W. Jafri

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


We determined the prevalence of Entamoeba (E.) histolytica, E. dispar and E. moshkovskii in patients with chronic diarrhoea associated with abdominal pain or discomfort mimicking irritable bowel syndrome. Stool samples were collected from 161 patients with chronic diarrhoea and from 157 healthy controls. Stool microscopy with modified trichrome stain, culture and polymerase chain reaction (PCR) for Entamoeba spp. differentiation was performed. Microscopy demonstrated Entamoeba cysts in 44% (57/129) of patients with diarrhoea compared to 29% (44/151) of controls (P=0.009). In patients with diarrhoea, PCR for E. histolytica was positive in 9% (11/129) (P=0.008), E. dispar in 19% (24/129) (P=0.117) and E. moshkovskii in 19% (24/129) (P<0.001). E. histolytica and E. moshkovskii were significantly associated with diarrhoea while E. dispar was found equally in both groups.

Original languageEnglish
Pages (from-to)323-328
Number of pages6
JournalEpidemiology and Infection
Issue number2
Publication statusPublished - Feb 2012


  • Diarrhoea
  • Entamoeba dispar
  • Entamoeba histolytica
  • Entamoeba moshkovskii
  • PCR


Dive into the research topics of 'Entamoeba species associated with chronic diarrhoea in Pakistan'. Together they form a unique fingerprint.

Cite this