Enterobacter sepsis in the newborn - a growing problem in Karachi

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Enterobactel sepsis is commonly recognized as a hospital-acquired infection in childhood. In a five year prospective surveillance of neonatal sepsis at the Aga Khan University Hospital in Karachi, we identified Enterobacter sepsis in 28/292 (10%) cases, with an incidence of 0.7 per thousand births among inborn infants. There was no significant difference in predisposing factors and clinical features between Enterobacter and other infections. Approximately half (47%) of Enterobacter infections presented within 72h of birth and the associated mortality was 21%. Increasing resistance to commonly used first- and second-line antibiotics over the last five years was noted. Enterobacter infections are emerging as significant pathogens among cases of neonatal sepsis in Karachi.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalJournal of Hospital Infection
Issue number3
Publication statusPublished - Nov 1996


  • Enterobacter
  • Neonatal sepsis
  • Resistance


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