Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee

Monique A. Foster; Junaid Iqbal; Chengxian Zhang; Rendie McHenry; Brent E. Cleveland; Yesenia Romero-Herazo; Chris Fonnesbeck; Daniel C. Payne; James D. Chappell; Natasha Halasa; Oscar G. Gómez-Duarte

doi:10.1016/j.diagmicrobio.2015.07.016

Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee

Monique A. Foster
, Junaid Iqbal
, Chengxian Zhang
, Rendie McHenry
, Brent E. Cleveland
, Yesenia Romero-Herazo
, Chris Fonnesbeck
, Daniel C. Payne
, James D. Chappell
, Natasha Halasa
, Oscar G. Gómez-Duarte

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

This prospective acute gastroenteritis (AGE) surveillance was conducted in the inpatient and emergency room settings at a referral pediatric hospital to determine the prevalence of diarrheagenic Escherichia coli (DEC) in children <12. years of age with AGE in Davidson County, Tennessee. Subjects 15 days to 11 years of age, who presented with diarrhea and/or vomiting, were enrolled. Stool specimens were processed for detection of DEC using multiplex polymerase chain reaction. From December 1, 2011, to June 30, 2012, a total of 79 (38%) out of 206 stool specimens from children with AGE tested positive for E. coli. A total of 12 (5.8%) out of 206 stool specimens from children with AGE were positive for a DEC. Eight (67%) out of these 12 were positive for enteropathogenic E. coli, and the remaining 4 were positive for enteroaggregative E. coli. DEC clinical isolates clustered with known E. coli enteropathogens according to multilocus sequencing typing.

Original language	English (US)
Pages (from-to)	319-324
Number of pages	6
Journal	Diagnostic Microbiology and Infectious Disease
Volume	83
Issue number	3
DOIs	https://doi.org/10.1016/j.diagmicrobio.2015.07.016
Publication status	Published - Nov 2015
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Children
Diarrhea
E. coli
EAEC
EPEC
Epidemiology
Gastroenteritis

Access to Document

10.1016/j.diagmicrobio.2015.07.016

Cite this

Foster, M. A., Iqbal, J., Zhang, C., McHenry, R., Cleveland, B. E., Romero-Herazo, Y., Fonnesbeck, C., Payne, D. C., Chappell, J. D., Halasa, N., & Gómez-Duarte, O. G. (2015). Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee. Diagnostic Microbiology and Infectious Disease, 83(3), 319-324. https://doi.org/10.1016/j.diagmicrobio.2015.07.016

@article{c75d73c96c764811b632b836048135fc,

title = "Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee",

abstract = "This prospective acute gastroenteritis (AGE) surveillance was conducted in the inpatient and emergency room settings at a referral pediatric hospital to determine the prevalence of diarrheagenic Escherichia coli (DEC) in children <12. years of age with AGE in Davidson County, Tennessee. Subjects 15 days to 11 years of age, who presented with diarrhea and/or vomiting, were enrolled. Stool specimens were processed for detection of DEC using multiplex polymerase chain reaction. From December 1, 2011, to June 30, 2012, a total of 79 (38\%) out of 206 stool specimens from children with AGE tested positive for E. coli. A total of 12 (5.8\%) out of 206 stool specimens from children with AGE were positive for a DEC. Eight (67\%) out of these 12 were positive for enteropathogenic E. coli, and the remaining 4 were positive for enteroaggregative E. coli. DEC clinical isolates clustered with known E. coli enteropathogens according to multilocus sequencing typing.",

keywords = "Children, Diarrhea, E. coli, EAEC, EPEC, Epidemiology, Gastroenteritis",

author = "Foster, \{Monique A.\} and Junaid Iqbal and Chengxian Zhang and Rendie McHenry and Cleveland, \{Brent E.\} and Yesenia Romero-Herazo and Chris Fonnesbeck and Payne, \{Daniel C.\} and Chappell, \{James D.\} and Natasha Halasa and G{\'o}mez-Duarte, \{Oscar G.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc..",

year = "2015",

month = nov,

doi = "10.1016/j.diagmicrobio.2015.07.016",

language = "English (US)",

volume = "83",

pages = "319--324",

journal = "Diagnostic Microbiology and Infectious Disease",

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}

Foster, MA, Iqbal, J, Zhang, C, McHenry, R, Cleveland, BE, Romero-Herazo, Y, Fonnesbeck, C, Payne, DC, Chappell, JD, Halasa, N & Gómez-Duarte, OG 2015, 'Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee', Diagnostic Microbiology and Infectious Disease, vol. 83, no. 3, pp. 319-324. https://doi.org/10.1016/j.diagmicrobio.2015.07.016

TY - JOUR

T1 - Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee

AU - Foster, Monique A.

AU - Iqbal, Junaid

AU - Zhang, Chengxian

AU - McHenry, Rendie

AU - Cleveland, Brent E.

AU - Romero-Herazo, Yesenia

AU - Fonnesbeck, Chris

AU - Payne, Daniel C.

AU - Chappell, James D.

AU - Halasa, Natasha

AU - Gómez-Duarte, Oscar G.

PY - 2015/11

Y1 - 2015/11

N2 - This prospective acute gastroenteritis (AGE) surveillance was conducted in the inpatient and emergency room settings at a referral pediatric hospital to determine the prevalence of diarrheagenic Escherichia coli (DEC) in children <12. years of age with AGE in Davidson County, Tennessee. Subjects 15 days to 11 years of age, who presented with diarrhea and/or vomiting, were enrolled. Stool specimens were processed for detection of DEC using multiplex polymerase chain reaction. From December 1, 2011, to June 30, 2012, a total of 79 (38%) out of 206 stool specimens from children with AGE tested positive for E. coli. A total of 12 (5.8%) out of 206 stool specimens from children with AGE were positive for a DEC. Eight (67%) out of these 12 were positive for enteropathogenic E. coli, and the remaining 4 were positive for enteroaggregative E. coli. DEC clinical isolates clustered with known E. coli enteropathogens according to multilocus sequencing typing.

AB - This prospective acute gastroenteritis (AGE) surveillance was conducted in the inpatient and emergency room settings at a referral pediatric hospital to determine the prevalence of diarrheagenic Escherichia coli (DEC) in children <12. years of age with AGE in Davidson County, Tennessee. Subjects 15 days to 11 years of age, who presented with diarrhea and/or vomiting, were enrolled. Stool specimens were processed for detection of DEC using multiplex polymerase chain reaction. From December 1, 2011, to June 30, 2012, a total of 79 (38%) out of 206 stool specimens from children with AGE tested positive for E. coli. A total of 12 (5.8%) out of 206 stool specimens from children with AGE were positive for a DEC. Eight (67%) out of these 12 were positive for enteropathogenic E. coli, and the remaining 4 were positive for enteroaggregative E. coli. DEC clinical isolates clustered with known E. coli enteropathogens according to multilocus sequencing typing.

KW - Children

KW - Diarrhea

KW - E. coli

KW - EAEC

KW - EPEC

KW - Epidemiology

KW - Gastroenteritis

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DO - 10.1016/j.diagmicrobio.2015.07.016

M3 - Article

C2 - 26298817

AN - SCOPUS:84943580997

SN - 0732-8893

VL - 83

SP - 319

EP - 324

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 3

ER -

Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee

Abstract

UN SDGs

Keywords

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