TY - JOUR
T1 - Etiological response and haematological and biochemical profiles of carp (Cyprinus carpio) exposed to trichlorfon
AU - Al-Ghanim, Khalid A.
AU - Al-Kahem Al-Balawi, Hmoud F.
AU - Al-Akel, Ali S.
AU - Al-Misned, Fahad
AU - Ahmad, Zubair
AU - Annazri, H.
PY - 2008
Y1 - 2008
N2 - Specimens of carp (Cyprinus carpio) exposed to different lethal and sublethal concentrations of trichlorfon showed restlessness, excess secretion of mucus, rapid body movements and difficulty in respiration. The LC50 values along with 95% fiducial lower and upper limit (in parentheses) for 24, 48, 72 and 96 h, computed from a probit graph for tested fish were 26.65 (26.03-27.17), 23.40 (22.55-24.30), 20.92 (20.26-21.61) and finally 18.74 (18.18-19.30) mg/l, respectively. Haematological parameters studied showed that the erythrocytes count, haemoglobin concentrations and haematocrit values increased whereas leukocytes count dropped down after trichlorfon exposure. Values of erythrocytic indices like MCV, MCH and MCHC also changed. Differential counts showed that the trichlorfon causes lymphopenia, thrombopenia and neutrophilia in the toxicant exposed fish. Level of glycogen in muscles and liver of fish decreased significantly (p<0.05) while glucose level increased remarkably after pesticide treatment. A significant reduction in the acetylcholinesterase (AChE) activity in the brain tissue of the fish exposed to trichlorfon was registered.
AB - Specimens of carp (Cyprinus carpio) exposed to different lethal and sublethal concentrations of trichlorfon showed restlessness, excess secretion of mucus, rapid body movements and difficulty in respiration. The LC50 values along with 95% fiducial lower and upper limit (in parentheses) for 24, 48, 72 and 96 h, computed from a probit graph for tested fish were 26.65 (26.03-27.17), 23.40 (22.55-24.30), 20.92 (20.26-21.61) and finally 18.74 (18.18-19.30) mg/l, respectively. Haematological parameters studied showed that the erythrocytes count, haemoglobin concentrations and haematocrit values increased whereas leukocytes count dropped down after trichlorfon exposure. Values of erythrocytic indices like MCV, MCH and MCHC also changed. Differential counts showed that the trichlorfon causes lymphopenia, thrombopenia and neutrophilia in the toxicant exposed fish. Level of glycogen in muscles and liver of fish decreased significantly (p<0.05) while glucose level increased remarkably after pesticide treatment. A significant reduction in the acetylcholinesterase (AChE) activity in the brain tissue of the fish exposed to trichlorfon was registered.
KW - AChE activity
KW - Carbohydrates
KW - Cyprinus carpio
KW - Haematology
KW - Toxicity
KW - Trichlorfon
UR - http://www.scopus.com/inward/record.url?scp=55249096720&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:55249096720
SN - 1459-0255
VL - 6
SP - 473
EP - 479
JO - Journal of Food, Agriculture and Environment
JF - Journal of Food, Agriculture and Environment
IS - 3-4
ER -