Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

Sara Iqbal; Humza Thobani; Saulat Fatimi

doi:10.4103/1995-7645.315892

Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

Sara Iqbal, Humza Thobani, Saulat Fatimi

Research output: Contribution to journal › Article › peer-review

Abstract

Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.

Original language	English
Pages (from-to)	231-233
Number of pages	3
Journal	Asian Pacific Journal of Tropical Medicine
Volume	14
Issue number	5
DOIs	https://doi.org/10.4103/1995-7645.315892
Publication status	Published - 1 May 2021
Externally published	Yes

Keywords

Extensive drug resistance
Immunocompetence
Osteomyelitis
Rib
Salmonella typhi

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10.4103/1995-7645.315892

Cite this

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title = "Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report",

abstract = "Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.",

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T1 - Extensively drug-resistant Salmonella typhi causing rib osteomyelitis

T2 - A case report

AU - Iqbal, Sara

AU - Thobani, Humza

AU - Fatimi, Saulat

PY - 2021/5/1

Y1 - 2021/5/1

N2 - Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.

AB - Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.

KW - Extensive drug resistance

KW - Immunocompetence

KW - Osteomyelitis

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KW - Salmonella typhi

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Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

Abstract

Keywords

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