Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

Sara Iqbal, Humza Thobani, Saulat Fatimi

Research output: Contribution to journalArticlepeer-review


Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.

Original languageEnglish
Pages (from-to)231-233
Number of pages3
JournalAsian Pacific Journal of Tropical Medicine
Issue number5
Publication statusPublished - 1 May 2021
Externally publishedYes


  • Extensive drug resistance
  • Immunocompetence
  • Osteomyelitis
  • Rib
  • Salmonella typhi


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