Factors associated with elevated serum cholesterol levels in well-to-do Pakistani schoolchildren

S. H. Badruddin, M. Khurshid, A. Molla, W. W.T. Manser, R. Lalani, C. W. Vellani

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Cholesterol (CH) and triglyceride (TG) levels were determined in blood drawn after an overnight fast from 388 school children aged 5-19 years from private schools in Karachi. The mean CH levels ranged from 4.4 to 4.6 mmol l-1 (170.1 to 177.9 mg dl-1) for boys and 4.4 to 4.8 mmol l-1 (170.1 to 185.6 mg dl-1) for girls. The range of TG levels was 1.0 to 1.2 mmol l-1 (88.6 to 106.3 mg dl-1) and 0.9 to 1.1 mmol l-1 (79.7 to 97.4 mg dl-1) for boys and girls respectively. Sixty-two per cent of the girls and 54% of the boys had cholesterol values ≥4.4 mmol l-1 (170 mg dl-1), a level at which dietary intervention is recommended for children. Thirty-two per cent of all the children had triglyceride levels above the 90th percentile of the levels for similar age groups in North America. The mean cholesterol intake was 469 mg/day for girls and 518 mg/day for boys. Overweight and inactivity were associated with raised serum cholesterol levels. Forty per cent of the girls and 25% of the boys reported a strong family history of hypercholesterolaemia and/or heart disease. The results show that the prevalence of hypercholesterolaemia is high in well-to-do Pakistani school children and factors which can be modified to lower serum cholesterol levels are identified.

Original languageEnglish
Pages (from-to)123-129
Number of pages7
JournalJournal of Tropical Medicine and Hygiene
Issue number2
Publication statusPublished - 1991


Dive into the research topics of 'Factors associated with elevated serum cholesterol levels in well-to-do Pakistani schoolchildren'. Together they form a unique fingerprint.

Cite this