Factors associated with month 2 smear non-conversion among Category 1 tuberculosis patients in Karachi, Pakistan

Kimberly A. D'Souza, Syed M.A. Zaidi, Maria Jaswal, Shahid Butt, Saira Khowaja, Shifa S. Habib, Amyn A. Malik

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Predictors of smear non-conversion at baseline can help identify cases at risk for failure of tuberculosis treatment. Retrospective data for smear-positive Category 1 patients in Karachi, Pakistan, was analyzed. Predictors of sputum conversion were determined using multiple logistic regression with sputum conversion as outcome variable and patient demographics, baseline weight, baseline sputum smear grade, case-finding approach as explanatory variables. Age ≥35 years, baseline sputum grade of 3+ were significantly associated with predicting sputum smear positivity at month 2 of treatment. Monitoring compliance to TB treatment should be considered amongst older patients and those with a high sputum grade at baseline.

Original languageEnglish
Pages (from-to)283-285
Number of pages3
JournalJournal of Infection and Public Health
Volume11
Issue number2
DOIs
Publication statusPublished - Mar 2018
Externally publishedYes

Keywords

  • Determinants
  • Non-conversion
  • Pakistan
  • TB
  • Treatment

Fingerprint

Dive into the research topics of 'Factors associated with month 2 smear non-conversion among Category 1 tuberculosis patients in Karachi, Pakistan'. Together they form a unique fingerprint.

Cite this